Results 91 to 100 of about 214,655 (309)

Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta

Clinical Pharmacology &Therapeutics, EarlyView.
Solute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Elijah Marsh Jung, Nicholas Ieronimakis, Bothaina Mousa, Emily D. Sheikh, Sarah E. Ligon, Joshua W. Monson, Jennifer R. Damicis, Hillary J. Kinsman, Lydia E. Bettridge, Samuel L.M. Arnold, Edward J. Kelly, Jashvant D. Unadkat, Joanne Wang   +12 more
wiley   +1 more source

Modulation of macrophage activation by prostaglandins

Mediators of Inflammation, 1996
The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor-α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration-dependent fashion, the lipopolysaccharide ...
L. Sautebin, R. Carnuccio, F. D'Acquisto, M. Di Rosa   +3 more
doaj   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Dietary Fish Oil and Zinc Reduced Plasma Prostaglandin E2 Content by Inhibiting Phospholipase A2 Production in Broilers

The Journal of Poultry Science, 2014
Two-factor experiment was designed to examine from lipid metabolism, proinflammatory eicosanoids, and lipid peroxidation for investigating the effects of dietary oils and zinc levels of cardiovascular system of broilers.
Guanzhong Liu, Shengying An, Jianmin Yuan, Yuming Guo, Dan Liu, Hui Chen, Renlu Huang   +6 more
doaj   +1 more source

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

Prostaglandin E2, its role in human organism

, 2017
Prostaglandin E2 je jedním z nejrozšířenějších zástupců skupiny prostaglandinů. Řadí se do skupiny lipidových mediátorů, které mohou prostřednictvím aktivace svých specifických receptorů regulovat široké spektrum jak fyziologických, tak i patologických ...
Fojtíková, Markéta
core   +1 more source

PROSTAGLANDIN Е₂ AS GULL TAPEWORM POTENTiAL iMMUNOMODULATOR

Acta Biomedica Scientifica, 2012
This article is devoted to investigation of prostaglandin E2 as potential immunomodulator of gull tapeworm. This parasite has an important epizootic and epidemiological significance in the Lake Baikal and. its basin.
I. A. Kutyrev, N. M. Biserova, J. P. Scharsack, J. .. Kurtz   +3 more
doaj  

Research progress on the role of prostaglandins in atopic dermatitis

Pifu-xingbing zhenliaoxue zazhi
Atopic dermatitis (AD) is a chronic inflammatory skin disease mediated by genetic, immune, and environmental factors. Prostaglandins (PGs), as critical lipid mediators, exert complex regulatory roles in AD.
WANG Mingxin, DONG Liping, XIAO Fengli
doaj   +1 more source

N-Acetylcysteine enhances the action of anti-inflammatory drugs as suppressors of prostaglandin production in monocytes

Mediators of Inflammation, 2002
The anti-inflammatory effect of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with inhibition of cyclooxygenase (COX), the rate-limiting enzyme responsible for the synthesis of prostaglandins.
Erica Hoffer, Yelena Baum, A. Menahem Nahir   +2 more
doaj   +1 more source

Human papillomavirus 16 L2 inhibits the transcriptional activation function, but not the DNA replication function, of HPV-16 E2 [PDF]

, 2005
In this study we analysed the outcome of the interaction between HPV-16 L2 and E2 on the transactivation and DNA replication functions of E2. When E2 was expressed on its own, it transactivated a number of E2-responsive promoters but co-expression of L2 ...
Morgan, I.M., Cordano, P., Taylor, E.R., Everett, R., R. Everett, A. Okoye, M.S. Campo, P. Cordano, E.R. Taylor, Campo, M.S., I.M. Morgan, Okoye, A.   +11 more
core   +1 more source