Results 81 to 90 of about 214,655 (309)

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Identification and characterization of prostaglandin F2α 9-dehydrogenase from Rhodotorula kratochvilovae

Applied Microbiology and Biotechnology
Prostaglandin F2α (PGF2α) is one of the most important bioactive lipids in mammals. Developing a bioproduction system for PGF2α could enable low-cost production with minimal environmental impact.
Ukyo Shino, Kazuki Yagi, Kei Munesato, Michiki Takeuchi, Ei-Tora Yamamura, Hideaki Nagano, Si-Bum Park, Hiroko Watanabe, Akinori Ando, Makoto Ueda, Jun Ogawa   +10 more
doaj   +1 more source

Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis.

PLoS ONE, 2019
BACKGROUND:Prostanoids are important regulators of platelet aggregation and thrombotic arterial diseases. Their involvement in the development of portal vein thrombosis, frequent in decompensated liver cirrhosis, is still not investigated.
Alexander Queck, Dominique Thomas, Christian Jansen, Yannick Schreiber, Sabrina Rüschenbaum, Michael Praktiknjo, Katharina Maria Schwarzkopf, Marcus Maximilian Mücke, Robert Schierwagen, Frank Erhard Uschner, Carsten Meyer, Joan Clària, Stefan Zeuzem, Gerd Geisslinger, Jonel Trebicka, Christian Markus Lange   +15 more
doaj   +1 more source

Decrease of prostaglandin E2 receptor binding is accompanied by reduced antilipolytic effects of prostaglandin E2 in isolated rat adipocytes.

Journal of Lipid Research, 1985
The effect of treatment of isolated rat adipocytes with prostaglandin E2 (PGE2) on subsequent [3H]PGE2 binding was studied. In addition, the antilipolytic effects of was studied. In addition, the antilipolytic effects of PGE2, adenosine, and insulin were
B Richelsen, H Beck-Nielsen
doaj   +1 more source

Prostaglandin E2 and Pain-An Update

Biological and Pharmaceutical Bulletin, 2011
Prostaglandin E(2) (PGE(2)), a cyclooxygenase (COX) product, is the best known lipid mediator that contributes to inflammatory pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), inhibitors of COX-1 and/or COX-2, suppress inflammatory pain by reducing generation of prostanoids, mainly PGE(2), while they exhibit gastrointestinal, renal and ...
openaire   +3 more sources

Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E2 in Pancreatic Tumors

, 2010
Prostaglandin E2 (PGE2) is a product of cyclooxygenase (COX) and PGE synthase (PGES) and deactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH).
Dawson, David W., Park, Jenny, Chen, Monica, Li, Aihua, Eibl, Guido, Reber, Howard A., Pham, Hung, Hines, O. Joe, King, Jonathan, Angst, Eliane   +9 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Role of the prostaglandin E2/E-prostanoid 2 receptor signalling pathway in TGFβ-induced mice mesangial cell damage

Bioscience Reports, 2014
The prostaglandin E2 receptor, EP2 (E-prostanoid 2), plays an important role in mice glomerular MCs (mesangial cells) damage induced by TGFβ1 (transforming growth factor-β1); however, the molecular mechanisms for this remain unknown.
Na‑Na Li, Yu‑Yin Xu, Xiao‑Lan Chen, Ya‑Ping Fan, Jian‑Hua Wu   +4 more
doaj   +1 more source

Polyphloretin phosphate temporarily potentiates prostaglandin E2 on the rat fundus, probably by inhibiting PG15-hydroxydehydrogenase

, 1973
Polyphloretin phosphate (PPP), an antagonist of some smooth muscle action of prostaglandins, potentiates the effect of prostaglandin E2 on the rat isolated stomach fundus preparation.
S M M Karim, P Adaikan Ganesan
core   +1 more source

Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]

, 2012
20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A, Gurbaxani, A, Taylor, SR, Lightman, S   +3 more
core   +1 more source