Results 111 to 120 of about 143,550 (306)

The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children

open access: yesBMC Pediatrics
Background Chronic inflammation and its control are crucial to the responses of glomerular and renal tubular cells. This contributes to the pathogenic mechanisms and advancement of the disease in Alport syndrome.
Moushira Zaki   +8 more
doaj   +1 more source

Stress induced experimental colitis

open access: yesMediators of Inflammation, 1993
Stress induces chemical changes in the central nervous system which alters the biochemistry and physiology of the digestive tract. The present study determines arachidonic acid oxidation and damage in the colon following stress. Ten rats were stressed by
T. A. Stein   +4 more
doaj   +1 more source

An observational study comparing two regimens of PGE2 gel for pre-induction cervical ripening at term [PDF]

open access: yesNew Indian Journal of OBGYN
Objectives: The objective of this study was to compare the outcome in between two groups, one group receiving a 6 hourly repeat regimen (maximum 2 such) and another group receiving a 12 hourly repeat regimen of prostaglandin E 2 gel (maximum 2 such ...
Nishat Parveen Begg   +2 more
doaj   +1 more source

Bronchoprotective role for endogenous prostaglandin E2

open access: yesThe Lancet, 1995
The possibility that impaired production of bronchoprotective factors contributes to the pathogenesis of asthma cannot be excluded. Prostaglandin E2 (PGE2) could be such a factor. It is a dominant cyclo-oxygenase product of airway epithelium and smooth muscle; it has inhibitory effects on inflammatory cells and pathways involved in bronchoconstriction ...
Pavord, I, Tattersfield, A
openaire   +3 more sources

Rehabilitation and return to activity after platelet‐rich plasma injections in chronic tendinopathies: Consensus from international experts

open access: yesPM&R, EarlyView.
Abstract Background The effectiveness of platelet‐rich plasma (PRP) injections in chronic tendinopathies remains debated. Although the product's characteristics play a role, the impact of postinjection recommendations remains poorly investigated. Objective To establish principles and guidelines for post‐PRP injection rehabilitation and return to ...
Vincent Gremeaux   +12 more
wiley   +1 more source

Pharmacological Effects of Prostaglandin E2 (PGE2)

open access: yesEurasian Journal of Medicine, 2019
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M.Nejat Gacar, Hasan Gacar
doaj  

Novel Therapeutics for Chronic Obstructive Pulmonary Disease: From Empirical Bronchodilation to Precision Medicine

open access: yesRespirology, EarlyView.
ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley   +1 more source

Oral misoprostol (PGE1) vs vaginal dinoprostone (PGE2) for labor induction: individual participant data meta‐analysis of randomized controlled trials

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of oral misoprostol vs vaginal dinoprostone for the induction of labor (IOL) using an individual participant data (IPD) meta‐analysis. Methods We used a Cochrane review and searched Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL Plus, Scopus and ClinicalTrials.gov to identify randomized ...
S. Y. Tan   +13 more
wiley   +1 more source

Prostaglandins in Cancer Cell Adhesion, Migration, and Invasion

open access: yesInternational Journal of Cell Biology, 2012
Prostaglandins exert a profound influence over the adhesive, migratory, and invasive behavior of cells during the development and progression of cancer.
David G. Menter, Raymond N. DuBois
doaj   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

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