Results 261 to 270 of about 394,079 (375)

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

Expression of Prostaglandin E2 Receptors in Acquired Middle Ear Cholesteatoma [PDF]

, 2017
Sujie Wang, Li Xie, Yanfei Zhang, Pengfei Xu, Aiguo Liu   +4 more
openalex   +1 more source

LRP4+ Astrocytes: A Unique Subpopulation Crucial for Blood Vessel Maintenance and Function in the Somatosensory Cortex of Normal and 5xFAD Mice

Glia, Volume 74, Issue 2, February 2026.
Lrp4+ astrocytes, uniquely vessel‐associated and GFAP−, are enriched in the pia. They support laminin‐α5+ basement membrane assembly and regulate vessel diameter and blood flow. They are reduced in 5xFAD brains, and their ablation worsens both vascular and Aβ pathology.
Emily Arzola, Gefei Yu, Lei Xiong, Daehoon Lee, Anika Wu, Shriya Paruchuri, Jasmine Skinner, Minghui Wang, Bin Zhang, Lin Mei, Wen‐Cheng Xiong   +10 more
wiley   +1 more source

Longan flower water extract promotes sleep in mice via the serotonin–melatonin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 3, Page 1852-1860, February 2026.
Abstract BACKGROUND Longan (Dimocarpus longan) flower is an underutilized botanical byproduct rich in polyphenols with reported neuroprotective actions, yet its role in sleep regulation remains unclear. This study aimed to evaluate the sleep‐promoting effects of longan flower water extract (LFWE) and its underlying neurochemical mechanisms in vivo ...
Tzu‐Huan Hung, Chiu‐Ping Cheng, Wei‐Chung Chiou, Tzu‐Lan Hsia, Hui‐Kang Liu, Hsu‐Feng Lu, Yu‐Heng Lai, Shang‐Ting Tsai, Chiung‐Ju Chen, Cheng Huang   +9 more
wiley   +1 more source

Cyclooxygenase-2/Prostaglandin E2 Pathway Facilitates Infectious Bronchitis Virus-Induced Necroptosis in Chicken Macrophages, a Caspase-Independent Cell Death. [PDF]

Viruses
Mahmoud ME, Tingley D, Faizal A, Ghaffar A, Azhar M, Salman D, Isham IM, Abdul-Careem MF.   +7 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Assessment of the Efficacy of Subgingivally Delivered Liquorice Gel on Clinical Parameters and Prostaglandin E2 Levels in Chronic Periodontitis: A Clinico-Biochemical Study. [PDF]

Cureus
Kumar Yadav B, Gupta D, Kumar Thakur R, Chauhan J, Mishra R, Kumar A.   +5 more
europepmc   +1 more source

An Inflammatory Mediator, Prostaglandin E2, in Colorectal Cancer

Cancer Journal, 2013
Dingzhi Wang, R. Dubois
semanticscholar   +1 more source

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2‐Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Aging Cell, Volume 25, Issue 2, February 2026.
A schematic showing decreased PTGES2 farnesylation in granulosa cells compromises PGE2‐dependent cumulus expansion and oocyte maturation during ovarian aging. In young ovaries, PTGES2 farnesylation of GCs regulates the process of cumulus expansion and oocyte maturation by facilitating PGE2 production.
Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun   +14 more
wiley   +1 more source

Myeloid Cells and Sensory Nerves Mediate Peritendinous Adhesion Formation via Prostaglandin E2. [PDF]

Adv Sci (Weinh)
Zhang X, Xiao Y, Tao Z, Zhang Y, Cheng X, Liu X, Li Y, Yin W, Tian J, Wang S, Zhang T, Yang X, Liu S.   +12 more
europepmc   +1 more source