Results 241 to 250 of about 143,781 (307)

Evaluation of Periodontal Clinicoradiographic Status and Whol Salivary Prostaglandin E2 Levels among Users of Water Pipe and Cigarettes. [PDF]

Oral Health Prev Dent
Almeslet AS, Aljudaibi SM, Alqhtani MAZ, Aseri AA, Alanazi SM.   +4 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Cyclooxygenase-2/prostaglandin E2 pathway orchestrates the replication of infectious bronchitis virus in chicken tracheal explants. [PDF]

Microbiol Spectr
Mahmoud ME, Ali A, Farooq M, Isham IM, Suhail SM, Herath-Mudiyanselage H, Rahimi R, Abdul-Careem MF.   +7 more
europepmc   +1 more source

Targeting Tumor Stroma: Current Challenges and Future Directions

MedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang   +7 more
wiley   +1 more source

MSC administration resolves experimental acute gout increasing specialized pro-resolving mediators synthesis through a super-induction of prostaglandin E₂. [PDF]

Stem Cell Res Ther
Bermejo-Álvarez I, Vázquez C, Irigaray-Moreno A, Quevedo-Romero I, Mediero A, Herrero-Beaumont G, Largo R.   +6 more
europepmc   +1 more source

Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases

MedComm, Volume 7, Issue 5, May 2026.
1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang, Jingjing Ge, Zehua Wang, Yihua Fang, Yongxu Jia, Ruyue Zhang, Yanru Qin   +6 more
wiley   +1 more source

Proliferative Diabetic Retinopathy Microenvironment Drives Microglial Polarization and Promotes Angiogenesis and Fibrosis via Cyclooxygenase-2/Prostaglandin E2 Signaling. [PDF]

Int J Mol Sci
Kishishita S, Usui-Ouchi A, Ouchi Y, Hata Y, Ebihara N, Nakao S.   +5 more
europepmc   +1 more source

Insights Into Bifenthrin Stereoisomers and Their Regulatory Implications

ChemistryOpen, Volume 15, Issue 5, May 2026.
Bifenthrin is a pyrethroid insecticide with two stereogenic centers, generating four stereoisomers with distinct physicochemical and electronic properties. A combined crystallographic and density functional theory study, supported by Hirshfeld surface, quantum theory of atoms in molecules, natural bond orbital, and reactivity descriptor analyses ...
Nayara C. M. Santos, Nayara D. Coutinho, Vitor S. Duarte, Anderson Catao, Antônio S. N. Aguiar, Lucas D. Dias, James O. Fajemiroye, Hamilton B. Napolitano   +7 more
wiley   +1 more source

The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population.

J Clin Endocrinol Metab
Geurts F, Rudolphi CF, Pelouto A, van der Burgh AC, Salih M, Imenez Silva PH, Fenton RA, Chaker L, Hoorn EJ.   +8 more
europepmc   +1 more source

Prostaglandin E₂-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth. [PDF]

Proc Natl Acad Sci U S A
Matsuura R, Punyawatthananukool S, Kawakami R, Mikami N, Sakaguchi S, Narumiya S.   +5 more
europepmc   +1 more source