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Prostaglandin E2 on the electroencephalogram
Prostaglandins, 1975Present study was prompted by the report from another center on the occasional occurrence of convulsions and abnormal electroencephalogram (E.E.G.) patterns in women aborted with intra-amniotic prostaglandin F2alpha (PGF2alpha). Fifty four subjects were investigated by means of an E.E.G. taken before and after initiation of PGE2 administration.
J J, Amy +3 more
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Prostaglandin E2 in Pyloric Stenosis
Archives of Surgery, 1989Prostaglandins are presumed to have many cytoprotective properties that play a role in the pathogenesis of duodenal ulcer and its complications where decreased levels of prostaglandin E2 (PGE2) impair gastric motility, oppose ionic membrane influx, and enhance obstructive changes. These are just some of the mechanisms that may cause pyloric obstruction
G, Goldman +6 more
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Pharmacogenetics and Genomics, 2007
Prostaglandin synthesis is the primary target of aspirin and other nonsteroidal antiinflammatory drugs, and thus is a pathway of major interest to pharmacology, pharmacogenetics, and epidemiology. Several lines of evidence implicate prostaglandin E2 in carcinogenesis; this study aimed to identify genetic variants in genes related to prostaglandin E2 ...
Jeannette, Bigler +5 more
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Prostaglandin synthesis is the primary target of aspirin and other nonsteroidal antiinflammatory drugs, and thus is a pathway of major interest to pharmacology, pharmacogenetics, and epidemiology. Several lines of evidence implicate prostaglandin E2 in carcinogenesis; this study aimed to identify genetic variants in genes related to prostaglandin E2 ...
Jeannette, Bigler +5 more
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Roles of prostaglandin E2 in the cochlea
Hearing Research, 2011Prostaglandins are one of the major groups of chemical mediators in the mammalian body. Among prostaglandins, prostaglandin E2 (PGE2) is the most abundant prostanoid in humans and involved in regulating many different fundamental biological functions. PGE2 signaling is mediated by four distinct E-prostanoid receptors (EPs) namely EP1-4.
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1995
Prostaglandin E2 is the most common and biologically potent of the primary prostaglandins. It induces contraction of uterine smooth muscle at all stages of pregnancy and is used principally to induce labour or as an abortifacient. It has vasodilator and bronch-odilator properties. It can be given by vaginal, oral and parenteral routes.
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Prostaglandin E2 is the most common and biologically potent of the primary prostaglandins. It induces contraction of uterine smooth muscle at all stages of pregnancy and is used principally to induce labour or as an abortifacient. It has vasodilator and bronch-odilator properties. It can be given by vaginal, oral and parenteral routes.
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Journal of Endocrinology, 1983
Abstract Intravenous injection of 6·7–60 μg of a stable prostaglandin E2 analogue, 16,16-dimethyl prostaglandin E2, into 10-day-old chicks caused profound, long-lasting hypercalcaemia. Simultaneous i.v. loading with 50 μmol Ca/bird enhanced the peak response. The responses were accompanied by sedation and lowered skin temperature. Use
G C, Kirby, C G, Dacke
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Abstract Intravenous injection of 6·7–60 μg of a stable prostaglandin E2 analogue, 16,16-dimethyl prostaglandin E2, into 10-day-old chicks caused profound, long-lasting hypercalcaemia. Simultaneous i.v. loading with 50 μmol Ca/bird enhanced the peak response. The responses were accompanied by sedation and lowered skin temperature. Use
G C, Kirby, C G, Dacke
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The antidipsogenic action of peripheral prostaglandin E2
Pharmacology Biochemistry and Behavior, 1981Intraperitoneal (IP) injection of 50 micrograms/kg prostaglandin E2 (PGE2) suppresses water intake elicited by cellular dehydration, intracerebroventricular injection of angiotensin II (A II) and, for a shorter duration, water deprivation. At a dose of 100 micrograms/kg, IP PGE2 reduces drinking to all of these stimuli as well as to hypovolemia.
N J, Kenney, K E, Moe, K M, Skoog
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Effect of Prostaglandin E2 on Adjuvant Arthritis
Nature, 1969THE prostaglandins are a class of cyclic, unsaturated, oxygenated fatty acids1,2 and their effects on capillary permeability3, corticosteroidogenesis4 and peripheral circulation5, as well as the prostaglandin-like activity found in inflammatory exudate6, suggested to us a possible therapeutic use in inflammatory conditions.
R L, Aspinall, P S, Cammarata
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