Results 281 to 290 of about 384,482 (373)

Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2

Proceedings of the National Academy of Sciences of the United States of America, 2012
Jianxiong Jiang, T. Ganesh, Yuhong Du, Yi Quan, G. Serrano, Min Qui, Iris A. Speigel, A. Rojas, N. Lelutiu, R. Dingledine   +9 more
semanticscholar   +1 more source

Lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during ischaemic contractions but not during freely perfused contractions

The Journal of Physiology, EarlyView.
Abstract figure legend The role of lactate and hydrogen ions in evoking the metabolic component of the exercise pressor reflex was studied in rats with either a functional pygm gene (pygm+/+) or with a non‐functional “knocked out” pygm gene (pygm−/−). The pygm gene is responsible for producing the myophosphorylase enzyme which catalyses the breakdown ...
Guillaume P. Ducrocq, Laura Anselmi, Victor Ruiz‐Velasco, Marc P. Kaufman   +3 more
wiley   +1 more source

The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population.

J Clin Endocrinol Metab
Geurts F, Rudolphi CF, Pelouto A, van der Burgh AC, Salih M, Imenez Silva PH, Fenton RA, Chaker L, Hoorn EJ.   +8 more
europepmc   +1 more source

Pharmacological evidence that the inhibitory effects of prostaglandin E2 are mediated by the EP2 and EP4 receptors in human neutrophils. [PDF]

J Leukoc Biol
Lavoie JC, Simard M, Kalkan H, Rakotoarivelo V, Huot S, Di Marzo V, Côté A, Pouliot M, Flamand N.   +8 more
europepmc   +1 more source

Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease

Annals of Neurology, 2012
Ju Shi, Qian Wang, J. Johansson, Xibin Liang, N. Woodling, Prachi G. Priyam, Taylor Loui, M. Merchant, R. Breyer, T. Montine, K. Andreasson   +10 more
semanticscholar   +1 more source

Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi‐Axial Perspective of Mechanical, Immune, and Metabolic Pathways

JOR SPINE, Volume 8, Issue 3, September 2025.
The senescence of NPCs is at the heart of the pathogenesis of intervertebral disc degeneration (IVDD), which causes low back discomfort. ABSTRACT Background The senescence of nucleus pulposus cells (NPCs) at the heart of the pathogenesis of intervertebral disc degeneration (IVDD), which causes low back pain.
Yunbo Yang, Haoming Li, Junhui Zuo, Fei Lei   +3 more
wiley   +1 more source

MAFB in Macrophages Regulates Prostaglandin E2-Mediated Lipid Mediator Class Switch through ALOX15 in Ischemic Acute Kidney Injury. [PDF]

J Immunol
Kanai M, Nishino T, Daassi D, Kimura A, Liao CW, Javanfekr Shahri Z, Wakimoto A, Gogoleva N, Usui T, Morito N, Arita M, Takahashi S, Hamada M.   +12 more
europepmc   +1 more source

Prostaglandin E2: A candidate for causative agent of "ogonori" poisoning.

, 1984
Nobuhiro Fusetani, Kanehisa HASHIMOTO
openalex   +2 more sources

Bioactive Compounds, Their Mechanisms of Action, and Cardioprotective Effects of Pomegranate (Punica granatum): A Comprehensive Review

eFood, Volume 6, Issue 4, August 2025.
Pomegranate parts (arils, peel, and flower) contain antioxidants, polyphenols, and flavonoids. These bioactives reduce inflammation, improve endothelial function, and modulate lipids. Regular intake lowers blood pressure, LDL, and atherosclerotic plaque while increasing HDL.
Esha Saeed, Farah Javed, Zoya Rana, Rashida Perveen, Iftikhar Younis Mallhi, Izza Amjad, Quratulain Maqsood, Nauman Ali Chaudhary, Saleha Binte Tahir, Arooj Fatima, Noor Fatima Rasheed, Esther Ugo Alum   +11 more
wiley   +1 more source

Dynamic changes in macrophage populations and resulting alterations in Prostaglandin E₂ sensitivity in mice with diet-induced MASH. [PDF]

Cell Commun Signal
Vahrenbrink M, Coleman CD, Kuipers S, Lurje I, Hammerich L, Kunkel D, Keye J, Dittrich S, Schjeide BM, Hiß R, Müller J, Püschel GP, Henkel J.   +12 more
europepmc   +1 more source