Results 281 to 290 of about 394,079 (375)

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir, Giada Giorgini, Irene Santos‐García, Elizabeth Dumais, Carmen Rodríguez‐Cueto, Eva de Lago, Cristoforo Silvestri, Nicolas Flamand, Javier Fernández‐Ruiz, Vincenzo Di Marzo   +9 more
wiley   +1 more source

Prostaglandin E₂-EP2/EP4 signaling induces the tumor-infiltrating Treg phenotype for tumor growth. [PDF]

Proc Natl Acad Sci U S A
Matsuura R, Punyawatthananukool S, Kawakami R, Mikami N, Sakaguchi S, Narumiya S.   +5 more
europepmc   +1 more source

Unlocking the Therapeutic Potential of Integrin‐Linked Kinase Inhibitors in Bioengineered 3D Breast Tumor Stroma Models

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
3D cancer models provide a more reliable representation of drug responses compared to 2D cell culture owing to their 3D architecture and facilitation of cell‐extracellular matrix interactions. In this study, we engineered dense compartmentalized 3D tumoroids composed of breast tumor mass and a surrounding stromal compartment replicating either breast ...
Salma T. Rafik, Anuja Upadhyay, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Evaluation of the covariation between leukotriene B4, prostaglandin E2, and hematologic inflammatory parameters in a canine pentylenetetrazole-induced seizure model. [PDF]

Front Neurosci
Koo Y, Yun T, Chae Y, Lee D, Kim H, Yang MP, Kang BT.   +6 more
europepmc   +1 more source

Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane

, 2012
D. Harland, Lora Lorenz, Kristin Fay, Bruce E. Dunn, Stephanie Gruenloh, Jayashree Narayanan, Elizabeth R. Jacobs, Meetha Medhora   +7 more
openalex   +2 more sources

Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2.

European journal of pharmaceutics and biopharmaceutics, 2013
V. Ivanova, O. Garbuzenko, K. Reuhl, D. Reimer, V. Pozharov, T. Minko   +5 more
semanticscholar   +1 more source

Pre‐Vascularized hMSC and hPDC Spheroids as Building Block Units for Bone Tissue Engineering

Advanced Materials Interfaces, Volume 13, Issue 2, 20 January 2026.
This study presents the development of small pre‐vascularized spheroids composed of human mesenchymal stromal cells or periosteum‐derived progenitor cells with endothelial cells. These microtissues demonstrated enhanced osteogenic and angiogenic potential, particularly with periosteum‐derived cells, and hold promise as building blocks for vascularized ...
Filipa C. Teixeira, Virginie Joris, Martijn van Griensven, Lorenzo Moroni, Carlos Mota   +4 more
wiley   +1 more source

Prostaglandin E2 affects mitochondrial function in adult mouse cardiomyocytes and hearts. [PDF]

Prostaglandins Leukot Essent Fatty Acids
Bryson TD, Zurek M, Moore C, Taube D, Datta I, Levin A, Harding P.   +6 more
europepmc   +1 more source

COMPARISON OF FOLEY CATHETER AND PROSTAGLANDIN E2 TABLETS FOR THE INDUCTION OF LABOR AT TERM

, 2013
Ana Daneva Markova, Marija Hadzi Lega, Milan Stefanović   +2 more
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, Volume 13, Issue 2, 9 January 2026.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source