Results 51 to 60 of about 214,655 (309)
Advanced Healthcare Materials, EarlyView.Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
Scientific Reports, 2021 Mesenchymal stem cells (MSCs) administered for therapeutic purposes can be activated by interferon-γ (IFN-γ) secreted from natural killer cells in injured tissues and exert anti-inflammatory effects.
Ryo Kanai +11 more
doaj +1 more source
Regulation of microsomal prostaglandin E2 synthase by cyclopentenone prostaglandins in colon cancer cells [PDF]
, 2006 Prostaglandin E2 is the major prostaglandin involved in colorectal carcinogenesis. The biosynthesis of prostaglandin E2 is accomplished by several terminal prostaglandin E synthases through catalytical conversion of the cyclooxygenase product ...
Yudina, Yulyana
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Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Removal of prostaglandin E2 and increased intraoperative blood pressure during modified ultrafiltration in pediatric cardiac surgery [PDF]
, 2009 ObjectiveWe investigated the relationship between serum prostaglandin E2 and intraoperative blood pressure in pediatric cardiac surgery with modified ultrafiltration.MethodsIn 35 consecutive patients (31.6 ± 26.8 months, 0.4–111 months, 10.9 ± 5.5 kg, 2 ...
Yokoyama, Kazuto +6 more
core +1 more source
Advanced Science, EarlyView.Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source
Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis
Advanced Science, EarlyView.A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa +5 more
wiley +1 more source
Effects of male attractiveness on prostaglandin E2 production levels [PDF]
, 2023 Sexual conflict or sexual antagonism can encourage co-evolution between males and females of a given species. In house crickets (Acheta domesticus), unattractive (smaller) and attractive (larger) males seem to use differential allocation of prostaglandin
Cousins, Kyra
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The Effects of Bee Venom on PLA2, COX-2, iNOS, AA and PG in RAW 264.7 Cells
Journal of Pharmacopuncture, 2002 Objectives : The purpose of this study was to investigate the effect of Bee Venom on the lipopolysaccharide-induced expression phospholipase A2, cyclooxygenase-2 and inducible nitrogen oxide synthase, and the generation of arachidonic acid, prostaglandin
Hyun-Chul Jo +3 more
doaj +1 more source
Caracterização farmacológica e molecular dos mecanismos envolvidos no edema de pata induzido pela prostaglandina E2 (PGE2) [PDF]
, 2006 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.
Claudino, Rafaela Franco
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