Results 121 to 130 of about 211,100 (336)

Attenuation of niacin-induced prostaglandin D2 generation by omega-3 fatty acids in THP-1 macrophages and Langerhans dendritic cells

Journal of Inflammation Research, 2012
Justin VanHorn1, Jeffrey D Altenburg1, Kevin A Harvey1, Zhidong Xu1, Richard J Kovacs2, Rafat A Siddiqui1,31Cellular Biochemistry Laboratory, Methodist Research Institute, Indianapolis, 2Krannert Institute of Cardiology, Indianapolis, 3Department of ...
VanHorn J, Altenburg JD, Harvey KA, Xu Z, Kovacs RJ, Siddiqui RA   +5 more
doaj  

Identification of Francisella novicida mutants that fail to induce prostaglandin E2 synthesis by infected macrophages.

Frontiers in Microbiology, 2013
Francisella tularensis is the causative agent of tularemia. We have previously shown that infection with F. tularensis Live Vaccine Strain (LVS) induces macrophages to synthesize prostaglandin E2 (PGE2). Synthesis of PGE2 by F.
Matthew Dale Woolard, Lydia M Barrigan, Lydia M Barrigan, James R Fuller, Adam S Buntzman, Joshua eBryan, Colin eManoil, Tom eKawula, Jeffrey A Frelinger   +8 more
doaj   +1 more source

Expression of oestrogen receptors, ERα, ERβ, and ERβ variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERα [PDF]

, 2009
Frances Collins, Sheila Macpherson, Pamela Brown, Vincent Bombail, Alistair Williams, Richard A. Anderson, Henry N. Jabbour, Philippa T. K. Saunders   +7 more
openalex   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Biomechanical Loading Modulates Proinflammatory and Bone Resorptive Mediators in Bacterial-Stimulated PDL Cells

Mediators of Inflammation, 2014
The present study aimed to evaluate in vitro whether biomechanical loading modulates proinflammatory and bone remodeling mediators production by periodontal ligament (PDL) cells in the presence of bacterial challenge. Cells were seeded on BioFlex culture
Andressa Vilas Boas Nogueira, Marjan Nokhbehsaim, Sigrun Eick, Christoph Bourauel, Andreas Jäger, Søren Jepsen, Carlos Rossa, James Deschner, Joni Augusto Cirelli   +8 more
doaj   +1 more source

New role for the anandamide metabolite prostaglandin F_2α ethanolamide: Rolling preadipocyte proliferation. [PDF]

J Lipid Res, 2023
Boubertakh B, Courtemanche O, Marsolais D, Di Marzo V, Silvestri C.   +4 more
europepmc   +1 more source

Constriction of Pial Arterioles Produced by Prostaglandin F _2α [PDF]

, 1975
William I. Rosenblum
openalex   +1 more source

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Stachydrine Ameliorates Uterine Hypercontractility in Primary Dysmenorrhea by Targeting the COX-2/PGF2α Pathway

Current Issues in Molecular Biology
Primary dysmenorrhea (PDM) is a typical gynecologic disease in which uterine contractions and inflammation cause pain. Stachydrine (Sta) possesses multiple pharmacological activities but its effect on PDM has not yet been clarified.
Yongfeng Cheng, Shuo Chen, Dianjie Cao, Hairu Cheng, Siyuan Chen, Yi Shu, Yue Wang, Zhiwu Chen   +7 more
doaj   +1 more source

Structures of human prostaglandin F_2α receptor reveal the mechanism of ligand and G protein selectivity. [PDF]

Nat Commun, 2023
Lv X, Gao K, Nie J, Zhang X, Zhang S, Ren Y, Sun X, Li Q, Huang J, Liu L, Zhang X, Zhang W, Liu X.   +12 more
europepmc   +1 more source