Results 191 to 200 of about 9,774,870 (350)

Exacerbation of Intracranial Aneurysm and Aortic Dissection in Hypertensive Rat Treated With the Prostaglandin F–Receptor Antagonist AS604872

open access: yesJournal of Pharmacological Sciences, 2014
.: Intracranial aneurysm (IA) and aortic dissection are both complications of hypertension and characterized by degeneration of the media. Given the involvement of prostaglandin F2α and its receptor, FP, in extracellular matrix remodeling in a mouse ...
Miyuki Fukuda   +8 more
doaj  

Solubilization of a prostaglandin F receptor in bovine corpora lutea [PDF]

open access: bronze, 1975
Sven Hammarstro ̈m   +3 more
openalex   +1 more source

Research progress of neurovascular units involved in ischemic stroke

open access: yesIbrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang   +4 more
wiley   +1 more source

Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase

open access: yesJournal of Lipid Research, 2013
Lipocalin prostaglandin D synthase (L-PGDS) regulates synthesis of an important inflammatory and signaling mediator, prostaglandin D2 (PGD2). Here, we used structural, biophysical, and biochemical approaches to address the mechanistic aspects of ...
Sing Mei Lim   +8 more
doaj  

Quasilinearization with Regularizing Tensor Paraproducts [PDF]

open access: yesarXiv
We construct an extension of the Bony quasilinearization formula as a tensor paraproduct decomposition to obtain an approximation, $\tilde{A}(f)$, to $A(f)$ where $f \in \text{tensor-} \Lambda^{\alpha}([0,1]^2)$ and $A \in C^2$. The rough content of $A(f)$ is encoded in the approximation of $\tilde{A}(f)$ while the residual, $\Delta(A,f) = A(f ...
arxiv  

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