Results 191 to 200 of about 9,718,735 (366)

Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish

Chemistry &Biodiversity, EarlyView.
ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel, Hortência Ribeiro Liberato, Antônio Wlisses da Silva, Maria Auxiliadora Solange Silva Gondim Pereira, Emanuela de Lima Rebouças, Francisco das Chagas L. Pinto, Matheus Nunes da Rocha, Maria Kueirislene Amâncio Ferreira, Janaina Serra Azul Monteiro Evangelista, Izabel Florindo Guedes, Marcia Machado Marinho, Emmanuel Silva Marinho, Andreia Ferreira de Castro Gomes, Otília Loiola Pessoa, Jane Eire Silva Alencar de Menezes, Hélcio Silva dos Santos   +15 more
wiley   +1 more source

A Novel UHPLC-MS/MS Method for Measuring 8-iso-Prostaglandin F_2α in Bronchoalveolar Lavage Fluid. [PDF]

Front Chem, 2021
Holder C, Adams A, Allison C, Cote O, Lippens R, Blount BC, Wang L.   +6 more
europepmc   +1 more source

Prostaglandins F in Uterine Tissue and Venous Plasma of Pseudopregnant Rats: Effect of Deciduomata [PDF]

, 1975
C.W. Weems, J.E. Pexton, R. L. Butcher, E. K. Inskeep   +3 more
openalex   +1 more source

Treatment With Phosphodiesterase 5 Inhibitors and Long‐Term Outcomes in Patients Undergoing Coronary Angiography and Cardiac Catheterization

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The effects of phosphodiesterase 5 (PDE5) inhibitors on the incidence of long‐term outcomes in patients with cardiovascular disease are not well understood. Objective: We studied the association between PDE5 inhibitor therapy and the incidence of adverse cardiovascular major adverse cardiovascular events (MACE) in patients ...
Sumon Roy, Annette Min, Edward O. McFalls, Robert A. Perera, Fadi N. Salloum, Ion S. Jovin   +5 more
wiley   +1 more source

The effects of prostaglandins E₁, F_1α and F_2α on monosynaptic reflexes

, 1968
P Duda, E. W. HORTON, Angus McPherson
openalex   +2 more sources

SWATH Differential Abundance Proteomics and Cellular Assays Show In Vitro Anticancer Activity of Arachidonic Acid- and Docosahexaenoic Acid-Based Monoacylglycerols in HT-29 Colorectal Cancer Cells [PDF]

, 2019
Colorectal cancer (CRC) is one of the most common and mortal types of cancer. There is increasing evidence that some polyunsaturated fatty acids (PUFAs) exercise specific inhibitory actions on cancer cells through different mechanisms, as a previous ...
Fabrikov, Dmitri, González Fernández, María José, Guil Guerrero, José Luis, Ortea, Ignacio, Ramos Bueno, Rebeca Pilar   +4 more
core   +1 more source

Comprehensive Analysis of Prostaglandin Metabolic Enzyme Expression During Pregnancy and the Characterization of AKR1B1 as a Prostaglandin F Synthase at the Maternal-Conceptus Interface in Pigs1

Biology of Reproduction, 2014
H. Seo, Yohan Choi, J. Shim, I. Yoo, H. Ka   +4 more
semanticscholar   +1 more source

Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering

ChemCatChem, EarlyView.
A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer, Erika Wedler, Carolin Mewe, Martin Gand, Marian Vogt, Lukas Korf, Lars‐Oliver Essen, Martin Rühl   +7 more
wiley   +1 more source

Exacerbation of Intracranial Aneurysm and Aortic Dissection in Hypertensive Rat Treated With the Prostaglandin F–Receptor Antagonist AS604872

Journal of Pharmacological Sciences, 2014
.: Intracranial aneurysm (IA) and aortic dissection are both complications of hypertension and characterized by degeneration of the media. Given the involvement of prostaglandin F2α and its receptor, FP, in extracellular matrix remodeling in a mouse ...
Miyuki Fukuda, Tomohiro Aoki, Toshiaki Manabe, Akiko Maekawa, Takayuki Shirakawa, Hiroharu Kataoka, Yasushi Takagi, Susumu Miyamoto, Shuh Narumiya   +8 more
doaj  

Comparison of Intra-CL Injection and Peripheral Application of Prostaglandin F_2α Analog on Luteal Blood Flow and Secretory Function of the Bovine Corpus Luteum. [PDF]

Front Vet Sci, 2021
Jonczyk AW, Piotrowska-Tomala KK, Skarzynski DJ.   +2 more
europepmc   +1 more source