Results 211 to 220 of about 9,718,735 (366)

Synthesis of 19‐Hydroxyarachidonic Acid by Fungal Peroxygenases: An Experimental and Computational Study

open access: yesChemSusChem, EarlyView.
An experimental and computational investigation on the regio‐ and enantioselective hydroxylation of arachidonic acid by several unspecific peroxygenases (UPOs) revealed rAaeUPO A77L variant as the most attractive candidate for the selective production of valuable hydroxy‐fatty acids because of its enhanced regio and enantioselectivity and reduced ...
Alejandro González‐Benjumea   +7 more
wiley   +1 more source

A Telescoped Strategy for the Preparation of Five‐Membered Hetero‐ and Carbocycles via Hydrogen Atom Transfer Photocatalysis in Flow

open access: yesChemSusChem, EarlyView.
Pyrroles, thiophenes, and cyclopentenones are vital in drug discovery, yet their synthesis via diversity oriented synthesis is limited. Herein, a modular platform is developed for the scalable, telescoped synthesis of named structures in continuous flow by streamlining photocatalyzed hydrogen atom transfer and Paal–Knorr or Hunsdiecker condensation ...
Filippo Sacchelli   +8 more
wiley   +1 more source

Structural and dynamic insights into substrate binding and catalysis of human lipocalin prostaglandin D synthase

open access: yesJournal of Lipid Research, 2013
Lipocalin prostaglandin D synthase (L-PGDS) regulates synthesis of an important inflammatory and signaling mediator, prostaglandin D2 (PGD2). Here, we used structural, biophysical, and biochemical approaches to address the mechanistic aspects of ...
Sing Mei Lim   +8 more
doaj  

Bioinformatics analysis of immune‐programmed cell death‐related genes in nasopharyngeal carcinoma

open access: yesEye &ENT Research, EarlyView.
Abstract Background Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor of the head and neck, characterized by a complex pathogenesis. Most newly diagnosed NPC patients are locally advanced, and 20%–30% of advanced NPC patients have poor immunotherapy results.
Hongqiang Chen   +3 more
wiley   +1 more source

Role of Prostaglandin F<SUB>2α</SUB> in Ovulation

open access: bronze, 1975
Toshikiyo Iesaka   +2 more
openalex   +2 more sources

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