Journal of Medicinal Chemistry, 2020 Idiopathic pulmonary fibrosis (IPF) is a rare and devastating chronic lung disease of unknown etiology. Despite the approved treatment options nintedanib and pirfenidone, the medical need for a safe and well tolerated anti-fibrotic treatment of IPF ...
H. Beck +21 more
semanticscholar +1 more source
Hypothyroidism Affects Uterine Function via the Modulation of Prostaglandin Signaling
Animals, 2021 Thyroid hormones control the functions of almost all body systems. Reproductive dysfunctions, such as abnormal sexual development, infertility, or irregularities in the reproductive cycle, might be associated with thyroid disorders.
Ilona Kowalczyk-Zieba +5 more
doaj +1 more source
Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]
, 2011 Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Nicolaou, A +3 more
core +7 more sources
Antioxidants, 2021 The liver is a key metabolic organ that is particularly sensitive to environmental factors, including UV radiation. As UV radiation induces oxidative stress and inflammation, natural compounds are under investigation as one method to counteract these ...
Michał Biernacki +2 more
doaj +1 more source
Effect of prostaglandin on reproduction in relation to pituitary gonadal axis in the fish, Cyprinus carpio (L.) [PDF]
, 2012 Prostaglandins are a class of fatty acids which are “traditionally” associated with a variety of autocrine and paracrine functions in the vertebrate body.
Dabhade, R.C. +2 more
core +2 more sources
Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers [PDF]
, 2003 Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA).
Adam, Olaf, Wolfram, G., Zöllner, N.
core +1 more source
Horses with equine recurrent uveitis have an activated CD4+ T-cell phenotype that can be modulated by mesenchymal stem cells in vitro. [PDF]
, 2020 Equine recurrent uveitis (ERU) is an immune-mediated disease causing repeated or persistent inflammatory episodes which can lead to blindness. Currently, there is no cure for horses with this disease.
Bellone, Rebecca R +6 more
core +1 more source
Animals, 2021 Intrauterine devices (IUDs) are used in mares to suppress oestrous behaviour, but the underlying mechanism is yet to be elucidated. The presence of an embryo or an IUD prevents cyclooxygenase-2 (COX-2) and, subsequently, prostaglandin (PG) release and ...
Maria Montserrat Rivera del Alamo +5 more
doaj +1 more source
Kinetic mechanism of ketoreductase activity of prostaglandin F synthase from bovine lung [PDF]
, 1993 The kinetic mechanism of ketoreductase activity of bovine lung prostaglandin F synthase, expressed in E. coli, was investigated. Data on initial velocity and radioisotope exchange between [3H]prostaglandin D; and 9α, 11β-prostaglandin F2 suggest that the
Barski, Oleg A., Watanabe, Kikuko
core +1 more source
A comparative study between prostaglandin F2α and methyl ergometrine in the active management of third stage of labour [PDF]
New Indian Journal of OBGYN, 2018 Objective: The aim of the study is to see the efficacy and safety of intramuscular Prostaglandin F 2α versus intravenous Methyl Ergometrine in active management of third stage labor. Material and Methods: A prospective study was carried out over a period
Sabha Malik +2 more
doaj +1 more source