Krisanaklan reduces CFTR‐dependent intestinal chloride and fluid secretion by inhibiting the Na+,K+‐ATPase and K+ channels in epithelial cells. Consequently, this natural, plant‐derived product may limit secretory diarrhea caused by a diverse array of microbial pathogens. However, by dissipating the transmembrane Na+ gradient, Krisanaklan also inhibits
Tessa A. Groeneweg +4 more
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Nuclear factor erythroid 2-related factor 2/heme oxygenase-1 activation by nattokinase reduces pro-inflammatory and matrix-degrading mediators in human gingival fibroblasts. [PDF]
Li YL +8 more
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Therapeutic Potential of <i>Irpex lacteus</i> Polysaccharides in Lupus Nephritis: Insights From Gut Microbiota and Metabolomics Analysis in MRL/Lpr Mice. [PDF]
Ji G +9 more
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Retraction for Murmu et al., Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E<sub>2</sub> in radiation damage. [PDF]
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PGE1 Suppresses the Expression of M2 Markers on Macrophages Through Prostaglandin Receptors. [PDF]
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Radioimmunoassay of the F Prostaglandins
The Journal of Clinical Endocrinology & Metabolism, 1971ABSTRACT Antibodies to prostaglandin F2α (PGF2α) were produced in rabbits immunized with a conjugate of PGF2α covalently linked to bovine serum albumin (BSA) by reaction with carbodiimide reagent. A radioimmunoassay was developed using dextran-coated charcoal to separate the free from antibody-bound PGF2α-3H. The sensitivity of the method was about 100
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Intramyometrial prostaglandin F2α
American Journal of Obstetrics and Gynecology, 1972Abstract Hypertonic saline and prostaglandin F 2α were injected into pregnant monkey myometrium. Small volumes of 20 per cent saline produced full-thickness myometrial necrosis with hemorrhage and thrombosis. PGF 2α in amounts sufficient to induce uterine contractions caused no histologic change.
A C, Wentz, T M, King
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Prostaglandin F2α Receptor-Dependent Regulation of Prostaglandin Transport
Molecular Pharmacology, 2001Prostaglandin (PG) F(2alpha) may act on its G protein-coupled receptor (FP) or be imported intracellularly via a transporter, which has high affinity for PGF(2alpha) and PGE(2), but not prostacyclin (PGI(2)). In cells overexpressing the epitope-tagged FP together with the human prostaglandin transporter (hPGT), stimulation of the FP with PGF(2alpha) (1
R, Vezza, J, Rokach, G A, FitzGerald
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