Results 21 to 30 of about 1,396,386 (296)

Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]

, 2012
20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A, Gurbaxani, A, Taylor, SR, Lightman, S   +3 more
core   +1 more source

Protective Effect of Prostaglandin EP4-Receptor Agonist on Anti-glomerular Basement Membrane Antibody-Associated Nephritis

Journal of Pharmacological Sciences, 2006
Prostaglandin E2-receptor subtypes, EP1, EP2, EP3, and EP4, are present in the kidney. The aim of this study was to elucidate the anti-nephritic effect of an EP4-receptor agonist on an experimental nephritic model. Mice were injected i.v.
Tadashi Nagamatsu, Hirohito Imai, Michiyo Yokoi, Tsutomu Nishiyama, Yasushi Hirasawa, Toshiyuki Nagao, Yoshio Suzuki   +6 more
doaj   +1 more source

Genetic risk variants in intestinal inflammatory disorders [PDF]

, 2010
PhDThis thesis includes work on the genetics of intestinal inflammatory disorders, concentrating on coeliac disease and Crohn’s disease. It explores how common genetic variants influence risk of complex phenotypes including immunological intolerance to
Dubois, Patrick Charles Alexander
core   +4 more sources

Endogenous inhibitory mechanisms in asthma

Journal of Allergy and Clinical Immunology: Global, 2023
Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E2, prostaglandin I2 ...
Sergio E. Chiarella, MD, Peter J. Barnes, MD   +1 more
doaj   +1 more source

Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia [PDF]

, 2009
<b>Background</b>: The majority of acute myeloid leukaemia (AML) patients are over sixty years of age. With current treatment regimens, survival rates amongst these, and also those younger patients who relapse, remain dismal and novel ...
Gunther Ulrich L., Gunther, U., Khanim, F.L., Alessia Lodi, Jim A Murray, Birtwistle Jane, Lodi, A, Chris, M., Gunther, Ulrich L., Khanim, Farhat L., Drayson, Mark T., Khanim Farhat L., Murray, James, Mountford, Joanne C., Murray, J.A., Ulrich L Gunther, Drayson, M., Tiziani, S, Gunther, U.L., Jane Birtwistle, Green Richard M., Farhat L Khanim, Bunce, Christopher, Hayden, R.E., Ride, Jon P., Murray, J., Mountford, J.C., Mark T Drayson, Davies, N., Schrewe, H., Stefano Tiziani, Drayson Mark T., Hayden, Rachel, Viant Mark R., Khanim, Farhat, Murray, Jim A., Davies, Nicholas, Lodi, A., Ride, Jonathan, Chris M Bunce, Gunther, Ulrich, Lodi, Alessia, Viant, Mark R., Tiziani, Stefano, Richard M Green, Viant, Mark; id_orcid, Mountford, JC, Ride, J.P., Joanne C Mountford, Green, Richard, Bunce Chris M., Heinrich Schrewe, Murray Jim A., Davies, Nicholas J., Drayson, Mark, Green, R., Schrewe, Heinrich, Mark R Viant, Davies Nicholas J., Jon P Ride, Mountford, J., Ride, J., Viant, M., Lodi Alessia, Drayson, M.T., Birtwistle, J., Hayden, Rachel E., Hayden Rachel E., Tiziani Stefano, Nicholas J Davies, Bunce, C.M., Ride Jon P., Hayden, R., Davies, N.J., Viant, M.R., Mountford Joanne C., Tiziani, S., Khanim, F., Birtwistle, Jane, Chris, M. Bunce, Schrewe Heinrich, Green, Richard M., Rachel E Hayden   +82 more
core   +1 more source

Colocalization of prostaglandin F2α receptor FP and prostaglandin F synthase-I in the spinal cord

Journal of Lipid Research, 2009
Prostaglandin F2α is synthesized by prostaglandin F synthase, which exists in two types, prostaglandin F synthase I (PGFS I) and prostaglandin F synthase II (PGFS II). Prostaglandin F2α binds to its specific receptor, FP. Our previous immunohistochemical
T. Suzuki-Yamamoto, K. Toida, Y. Sugimoto, K. Ishimura   +3 more
doaj   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Geisslinger, Gerd, Rolf M. Nusing, Gerd Geisslinger, Scholich, Klaus, Angioni, Carlo Federico, Klaus Scholich, Laura Popp, Brenneis, Christian, Ovidiu Coste, Becker, Wiebke, Popp, Laura, Nusing, Rolf M., Coste, Ovidiu, Carlo Angioni, Christian Brenneis, Ronald Schmidt, Wiebke Becker, Schmidt, Ronald   +17 more
core   +1 more source

G Protein-Coupled Receptor Genes, PTGDR1, PTGDR2, and PTGIR, Are Candidate Epigenetic Biomarkers and Predictors for Treated Patients with HPV-Associated Oropharyngeal Cancer

Microorganisms, 2020
Differences in the biology of human papillomavirus (HPV)-associated oropharyngeal cancers (OPCs) and HPV-negative OPCs may have implications in patient management. Early detection is imperative to reduce HPV-associated OPC mortality.
Kiyoshi Misawa, Atsushi Imai, Takeharu Kanazawa, Masato Mima, Satoshi Yamada, Daiki Mochizuki, Taiki Yamada, Daichi Shinmura, Ryuji Ishikawa, Jyunya Kita, Yuki Yamaguchi, Yuki Misawa, Hiroyuki Mineta   +12 more
doaj   +1 more source

Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells [PDF]

, 2009
Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine
Abera, Aron Berhanie
core   +1 more source

Anti-platelet therapy: ADP receptor antagonists. [PDF]

, 2011
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD, Stan Heptinstall, Yanushi Dullewe Wijeyeratne   +3 more
core   +1 more source