Results 31 to 40 of about 1,396,386 (296)

Improved homology modeling of the human & rat EP4 prostanoid receptors

BMC Molecular and Cell Biology, 2019
Background The EP4 prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E2 (PGE2). Novel selective EP4 receptor agonists would assist to further elucidate receptor sub-type function and promote development of ...
Melissa C. Holt, Chi S. Ho, M. Inés Morano, Stephen D. Barrett, Adam J. Stein   +4 more
doaj   +1 more source

AZAPROSTANOID PROBES FOR THE THROMBOXANE A2/PROSTAGLANDIN H2 PLATELET RECEPTOR.

, 1986
AZAPROSTANOID PROBES FOR THE THROMBOXANE A2/PROSTAGLANDIN H2 PLATELET ...
KATHRYN ELIZABETH. SCHNORF (7971845)
core   +6 more sources

Prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.

PLoS ONE, 2020
ObjectiveTo evaluate the prescribing trends of glaucoma drugs in six major cities of China from 2013 to 2017.MethodsA descriptive analysis using pharmacy prescription data was conducted.
Lingyan Yu, Kai Ding, Lifang Luo, Zhenwei Yu   +3 more
doaj   +1 more source

The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin-1ß [PDF]

, 2007
CRH targets the human myometrium during pregnancy. The efficiency of CRH actions is determined by expression of functional receptors (CRH-R), which are dynamically regulated.
Gu, Mei, Grammatopoulos, Dimitris, Markovic, Danijela, Slater, Donna, Newton, Rob, Vatish, Manu, Lehnert, Hendrik   +6 more
core   +1 more source

Female Type 1 Diabetic Akita Mice Demonstrate Increased Bladder Contractility via FP Receptor Activation due to NLRP3-Mediated Inflammation

Frontiers in Bioscience-Landmark
Background: Diabetic bladder dysfunction (DBD) is driven in part by inflammation which dysregulates prostaglandin release in the bladder. Precise inflammatory mechanisms responsible for such dysregulation have been elusive.
Michael R. Odom, Francis M. Hughes Jr., NiQuava Pope, Huixia Jin, J. Todd Purves   +4 more
doaj   +1 more source

Anti-inflammatory effects of the prostaglandin D2/prostaglandin DP1 receptor and lipocalin-type prostaglandin D2 synthase/prostaglandin D2 pathways in bacteria-induced bovine endometrial tissue

Veterinary Research, 2022
Dairy cows often develop different degrees of endometritis after calving and this is attributed to pathogenic bacterial infections such as by Escherichia coli and Staphylococcus aureus.
Jindi Wu, Fan Bai, Wei Mao, Bo Liu, Xiaolin Yang, Jing Zhang, Tingting Li, Gerelt Borjigin, Jinshan Cao   +8 more
doaj   +1 more source

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R, Thomas Haberberger, Carol M. Black, Haberberger, T, Xu Shiwen, Martini, G, Holmes, A, Alan Holmes, Andrew Leask, Shiwen, X, David Abraham, Black, CM, Leask, A, Martin, GR, Abraham, D, George R. Martin, Richard Stratton, Giorgia Martini   +17 more
core   +1 more source

Prostaglandins: Key players in immunomodulation of the nervous system

Neural Regeneration Research
As a class of bioactive substances that play important roles in a variety of physiological and pathological processes, prostaglandins have attracted increasing research attention.
Ziqin Wang, Ying Sun, Minjie Luo, Nina He, Zhongchi Wen, Zuzhen Wang, Yonglong Zhang, Jie Zhao, Ying Liu   +8 more
doaj   +1 more source

Relaxant Effect of Prostaglandin D2–Receptor DP Agonist on Liver Myofibroblast Contraction

Journal of Pharmacological Sciences, 2011
.: Increased intrahepatic resistance causes portal hypertension in cirrhosis. Liver myofibroblasts (MFs) are now regarded as the principle cells involved in sinusoidal blood flow regulation.
Tomoharu Maruyama, Shinya Ayabe, Takahisa Murata, Masatoshi Hori, Hiroshi Ozaki   +4 more
doaj   +1 more source

Activation of α7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E₂ in rat microglial cultures

Journal of Neuroinflammation, 2005
Background Nicotinic acetylcholine (Ach) receptors are ligand-gated pentameric ion channels whose main function is to transmit signals for the neurotransmitter Ach in peripheral and central nervous system.
Minghetti Luisa, Carnevale Daniela, Ajmone-Cat Maria, De Simone Roberta   +3 more
doaj   +1 more source