Antinociceptive and Anti‐inflammatory Effect of Nicandrin B Isolated From Datura ferox in Zebrafish
Chemistry &Biodiversity, EarlyView.ABSTRACT Nicandrin B (Nic B), a withanolide isolated from Datura ferox leaves, was investigated for its antinociceptive and anti‐inflammatory effects in adult zebrafish (Danio rerio). Animals treated with Nic B (4, 20, and 40 mg/kg) showed no toxicity and maintained normal locomotor activity.
Jéssica Bezerra Maciel +15 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background The effects of phosphodiesterase 5 (PDE5) inhibitors on the incidence of long‐term outcomes in patients with cardiovascular disease are not well understood. Objective: We studied the association between PDE5 inhibitor therapy and the incidence of adverse cardiovascular major adverse cardiovascular events (MACE) in patients ...
Sumon Roy +5 more
wiley +1 more source
Isolation of Prostaglandin E1 from Calf Thymus. Prostaglandins and Related Factors. 20. [PDF]
, 1963 Sune Bergström +2 more
openalex +1 more source
Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering
ChemCatChem, EarlyView.A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer +7 more
wiley +1 more source
Synthesis of Tritium-labeled Prostaglandin E2 and Studies on Its Metabolism in Guinea Pig Lung
, 1965 Erik Änggård +2 more
openalex +1 more source
THE EFFECTS OF PROSTAGLANDINS E1 AND E2 ON THE SMOOTH MUSCLE OF THE DOG SPLEEN AND ON ITS RESPONSES TO CATECHOLAMINES, ANGIOTENSIN AND NERVE STIMULATION [PDF]
, 1968 B. N. Davies, P.G. Withrington
openalex +1 more source
Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes
ChemElectroChem, EarlyView.This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský +5 more
wiley +1 more source
Chagas disease: Present status of pathogenic mechanisms and chemotherapy
Biological Research, 2010 There are approximately 7.8 million people in Latin America, including Chile, who suffer from Chagas disease and another 28 million who are at risk of contracting it. Chagas is caused by the flagellate protozoan Trypanosoma cruzi. It is a chronic disease,
Juan Diego Maya +5 more
doaj
Effects of infusion of some prostaglandins in essential fatty acid-deficient and normal rats
, 1968 Floyd P. Kupiecki +2 more
openalex +1 more source
Effect of prostaglandin E1 on the strychnine-induced convulsion in the mouse [PDF]
, 1969 Suna Duru, R. K. Türker
openalex +1 more source