EFFECTS OF PROSTAGLANDIN E2 AND A PROSTAGLANDIN ENDOPEROXIDE ANALOGUE ON NEUROEFFECTOR TRANSMISSION IN THE RAT ANOCOCCYGEUS MUSCLE [PDF]
KHAWLA S. AL TIMIMI+2 more
openalex +1 more source
Shifting the Substrate Scope of an Ene/Yne‐Reductase by Loop Engineering
A flexible active‐site loop that is involved in shaping the substrate and product cleft as well as the active‐site pocket was identified for the MDR‐related ene/yne‐reductase CaeEnR1 from Cyclocybe aegerita. Double mutations of this loop showed an up to 20‐fold increase in conversion rates toward cinnamaldehyde‐like substrates and a 2‐fold increase in ...
Dominik Karrer+7 more
wiley +1 more source
Effect of Escherichia coli infection of the bovine uterus from the whole animal to the cell*
Following parturition, contamination of the uterine lumen by bacteria is ubiquitous, and uterine health is impaired in cattle because infection persists in 10% to 15% of animals as endometritis.
E.J. Williams+5 more
doaj
Specific Binding of Prostaglandins E2and F2αby Membrane Preparations from Rat Skin* [PDF]
Jonathan T. Lord+2 more
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Cutting‐Edge Aptasensing Approaches for Electrochemical Detection of Exosomes Utilizing MXenes
This work notably summarizes research on 2D MXenes/MXene's‐hybrid‐based nanoplatforms patterned with aptamers as an alternative to antibodies affording highly sensitive and robust biosensing of exosomes as well as their efficient isolation. The exosomes are highlighted as a valuable source of biomarkers and with the immobilization approaches of ...
Andrej Vikartovský+5 more
wiley +1 more source
THE EFFECTS OF PROSTAGLANDINS E1, E2 AND F2α ON THE CUTANEOUS VASCULATURE OF THE RAT [PDF]
Loris A. Chahl, Rachel Ladd
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Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia+4 more
wiley +1 more source
Mass spectrometry in ocular drug research
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo+6 more
wiley +1 more source
THE RELEASE OF PROSTAGLANDIN E2 FROM THE SKIN OF THE PLAICE, Pleuronectes platessa L. [PDF]
Alison Anderson+2 more
openalex +1 more source