Results 331 to 340 of about 18,716,571 (404)
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Journal of the American Chemical Society, 1971
This is an explanation of 2 highly specific reductive processes for the interconversion of primary PGs (prostaglandins). The laboratory procedures are described in detail and the chemical structures of substances involved in the process are diagrammed. A stereospecific reduction of PGE to PGFalpha is described.
E J, Corey, R K, Varma
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This is an explanation of 2 highly specific reductive processes for the interconversion of primary PGs (prostaglandins). The laboratory procedures are described in detail and the chemical structures of substances involved in the process are diagrammed. A stereospecific reduction of PGE to PGFalpha is described.
E J, Corey, R K, Varma
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Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of receptor subtypes (EP1-EP4) to elicit its diverse actions including pyrexia, pain sensation, and inflammation.
Kohichi, Kawahara +4 more
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Prostaglandin E receptors and the kidney
American Journal of Physiology-Renal Physiology, 2000Prostaglandin E2is a major renal cyclooxygenase metabolite of arachidonate and interacts with four G protein-coupled E-prostanoid receptors designated EP1, EP2, EP3, and EP4. Through these receptors, PGE2modulates renal hemodynamics and salt and water excretion. The intrarenal distribution and function of EP receptors have been partially characterized,
M D, Breyer, R M, Breyer
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Prostaglandin e biosynthesis during cardiopulmonary bypass
Journal of Surgical Research, 1978Abstract Initiation of cardiopulmonary bypass (CPB) causes immediate drop in blood pressure and peripheral vascular resistance (PVR) with activation of complex neurohumoral reflex mechanisms and redistribution of systemic blood flow. Prostaglandin E (PGE) is a potent vasodilator released during ischemia and low flow states. This study was designed to
C R, Saunders +3 more
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Prostaglandin E in peptic ulcer disease
Prostaglandins, 1974Abstract Prostaglandin E 1 and E 2 inhibit gastric secretion in vivo and in vitro under a variety of conditions. It is not known whether these compounds may play a role in normal gastric secretory physiology or in the pathophysiology of peptic ulcer disease.
J G, Hinsdale, J J, Engel, D E, Wilson
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Biochemical and Biophysical Research Communications, 1997
Prostaglandin (PG) E synthase was found to be widely distributed in the microsomal fractions of rat organs. Among them, an extremely high activity was seen in the deferent duct (112 nmol/min x mg) and other genital accessory organs (10-20 nmol/min x mg). In non-genital organs, the kidney had the highest activity (8 nmol/min x mg).
K, Watanabe +3 more
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Prostaglandin (PG) E synthase was found to be widely distributed in the microsomal fractions of rat organs. Among them, an extremely high activity was seen in the deferent duct (112 nmol/min x mg) and other genital accessory organs (10-20 nmol/min x mg). In non-genital organs, the kidney had the highest activity (8 nmol/min x mg).
K, Watanabe +3 more
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Pharmacocavernometry with Prostaglandin E(1)
European Urology, 1993The aim of this study was to define the normal response of cavernometry parameters with high-dose pharmacostimulation, to investigate repeatability of the method and to find out the incidence of cavernovenous leakage in impotence. 82 consecutive impotent patients and 10 potent control subjects underwent pharmacocavernometry with 40 micrograms of ...
H O, Nisén, M L, Ruutu
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19-HydroxyIated E prostaglandins as the major prostaglandins of human semen
Nature, 1974ALMOST 30 years after the initial discovery of the prostaglandins, Bergstrom et al., succeeded in isolating and identifying prostaglandins (PGs) E1, E2, F1α and F2α from sources including human semen1. It was subsequently claimed2 that the 19-hydroxy derivatives of prostaglandins A and B were also present. These compounds were later found at an average
P L, Taylor, R W, Kelly
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Journal of Endocrinological Investigation, 1980
Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A, Isidori +4 more
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Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A, Isidori +4 more
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Prostaglandin E antagonist activity of 11,15-bisdeoxy prostaglandin E1 and congeners
Prostaglandins, 1977d,l-11, 15-bisdeoxy PGE1 and certain of its congeners were shown to inhibit gerbil colon contractions induced by l-PGE1. While some of these compounds were selectively antagonistic of PGE1-induced contractions, others additionally inhibited the gerbil colon agonist activities of l-PGE2alpha and acetylcholine. The PGE1 inhibitory activity was apparently
E L, Tolman, R, Partridge, E T, Barris
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