Results 101 to 110 of about 52,245 (306)

Inhibition of cytosolic Phospholipase A₂ prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin

BMC Neuroscience, 2012
Background Activation of phospholipase A2 (PLA2) and the subsequent metabolism of arachidonic acid (AA) to prostaglandins have been shown to play an important role in neuronal death in neurodegenerative disease.
Last Victoria, Williams Alun, Werling Dirk   +2 more
doaj   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

A comparison of the free radical scavenging activity of leukotrienes and prostaglandins [PDF]

, 1988
The relative reactivity of leukotrienes and prostaglandins to free radicals and the superoxide ion generated by the photo oxidation of dianisidine have been assessed in vitro.
M. Chopra, J. J. F. Belch, Smith, W. E., W. E. Smith, Chopra, M., Belch, J. J. F.; id_orcid   +5 more
core   +1 more source

Prostaglandins F₂α and E₂ in rat placenta and fetal membrane: a comprehensive immunohistochemistry of their synthetic enzymes and in vivo tissue levels during normal pregnancy. [PDF]

J Vet Med Sci, 2021
Satoh H, Terashima R, Kawaminami M, Kurusu S.   +3 more
europepmc   +1 more source

Super‐Multiplexed Label‐Free Raman Imaging Uncovers Novel Testicular Metabolic Couplings for Residual Body and Spermatogonial Differentiation

Advanced Science, EarlyView.
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li, Xia Chen, Yujuan Qi, Chen Qiao, Qiuru Huang, Dan Zhao, Weiyi Qian, Li Di, Yi Shi, Xiangqi Hu, Yueyue Shao, Kehan Wang, Zhiyu Tang‐Yang, Hanzhi Zang, Yuwen Du, Anran Dong, Jinxiong Feng, Jiayun Chen, Ying Zheng, Xiaofang Tan, Xiaoyu Zhao, Zhonghua Shi, Bo Zheng, Jun Yu   +23 more
wiley   +1 more source

Arachidonic acid and prostaglandins stimulate the growth of primary neonatal rat hepatocytes [PDF]

, 1981
Arachidonic acid and prostaglandins stimulate the growth of primary neonatal rat hepatocytes in ...
J. F. WHITFIELD, P. G. ANDREIS, ARMATO, Ubaldo   +2 more
core  

Prostaglandins do not mediate arteriolar oxygen reactivity [PDF]

, 1986
The hypothesis that prostaglandins mediate arteriolar O2 reactivity was tested by assessing the effects of cyclooxygenase and phospholipase A2 inhibitors on the O2 responses of arterioles in superfused hamster cheek pouch and hamster and rat cremaster ...
W. F. Jackson
core   +1 more source

Efficacy of Foley Catheter Bulb with Intracervical Dinoprostone Gel versus Dinoprostone Gel Alone for Cervical Ripening and Induction of Labour: An Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: One of the most common obstetrical interventions is the induction of labour. Cervical ripening drugs are typically used before conventional methods of induction since they are linked to an increased risk of protracted labour ...
Sohan Bhowmick, Nilratan Das, Tanmoy Das, Arunava Biswas   +3 more
doaj   +1 more source

IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α

Animal Models and Experimental Medicine, EarlyView.
IRF‐1 modulates hepatic ferroptosis and aggravates liver ischemia/reperfusion injury via DYRK1α. Abstract Background The purpose is to define the contribution of the interferon regulatory factor‐1–dual‐specificity tyrosine phosphorylation‐regulated kinase 1α (IRF‐1–DYRK1α) axis to hepatocellular ferroptosis during liver ischemia/reperfusion injury ...
Jinping Zhang, Jinming Zhang, Siyuan Song, Mingyang Li, Liying Sun, Zhijun Zhu, Dongdong Lin   +6 more
wiley   +1 more source

Niacin skin-flush response and electrodermal activity in patients with schizophrenia and healthy controls [PDF]

, 2006
Patients with schizophrenia have in different studies shown reduced niacin sensitivity and lower electrodermal activity (EDA) after auditory stimulation. Peripheral mediation of prostaglandins may have a physiological role in both responses.
Wiesel, Fritz-Axel,, Hultman, Christina, Nilsson, BM, Wiesel, F-A, B.M. Nilsson, Hultman, Christina M, Nilsson, Björn M,, Hultman, CM, F.-A. Wiesel, Nilsson, Björn Mikael,, C.M. Hultman, Wiesel, Frits-Axel,   +11 more
core   +1 more source