ABSTRACT Antibodies against HPV proteins can provide pre‐diagnostic information about cancer development. We described the prevalence of antibodies to proteins of oncogenic HPV types prior to diagnosis of HPV‐related cancers. We analysed pre‐diagnostic blood from 1700 participants with incident HPV‐related cancers (anal = 387, cervical = 274 ...
Justina Ucheojor Onwuka +28 more
wiley +1 more source
Incidence and oncologic outcomes of patients with prostate-specific antigen persistence after radical prostatectomy. [PDF]
Lane BR +13 more
europepmc +1 more source
MLH1 p.His112Arg Variant Is Associated With Increased Cancer Susceptibility
ABSTRACT Lynch syndrome, a prevalent hereditary cancer predisposition, is frequently caused by pathogenic variants in the MutL homolog 1 (MLH1) mismatch repair gene. However, a significant proportion of MLH1 missense variants remain classified as variants of uncertain significance (VUS), creating clinical ambiguity.
Amal Elfatih +10 more
wiley +1 more source
Prostate-Specific Antigen Screening Patterns and Metastatic Prostate Cancer in US Veterans.
Siavoshi M +12 more
europepmc +1 more source
Real-World Early Prostate-Specific Antigen Response Comparison Among Patients with Metastatic Castration Sensitive Prostate Cancer Treated with Apalutamide or Abiraterone Acetate in the United States. [PDF]
Lowentritt B +8 more
europepmc +1 more source
ABSTRACT Globally, Japan has the largest proportion of individuals aged ≥ 85 years. However, epidemiological studies on cancer in this age group are limited. This study aimed to investigate cancer trends and characteristics among the oldest‐old adults (aged ≥ 85 years) in Japan, using population‐based national and prefectural cancer registry data on ...
Sayo Tanaka +2 more
wiley +1 more source
Apalutamide-induced prostate-specific antigen response and its association with clinical outcomes in metastatic castration sensitive prostate cancer (Review). [PDF]
N S +8 more
europepmc +1 more source
ABSTRACT Medication taken for other reasons than for the treatment of malignant disease, termed concomitant medication, is known to affect outcomes when used with immune checkpoint inhibitor therapy and other oncological drugs. However, no research in humans has addressed the relationship between concomitant medications and efficacy of oncolytic ...
Santeri A. Pakola +20 more
wiley +1 more source
Prostate Specific Antigen Ordering After Implementation of a Point-of-Care Reminder to Discuss Screening. [PDF]
Fenton JJ, Tancredi DJ.
europepmc +1 more source
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang +10 more
wiley +1 more source

