Results 251 to 260 of about 366,020 (324)

Organ‐sparing strategies in patients with MSI/dMMR tumors including Lynch syndrome: Current state of the art and future perspectives for clinical decision‐making

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Deficiency in DNA mismatch repair (dMMR) is a common pathway of carcinogenesis across different tumor types and confers a characteristic microsatellite instability‐high (MSI‐H) molecular phenotype. The MSI‐H/dMMR phenotype may arise from an inherited pathogenic variant in the context of Lynch syndrome and is most frequently observed in ...
Martin Duval   +8 more
wiley   +1 more source

Minimizing quantification uncertainty in nanoplasmonic platforms: Multifunctional MoS2‐integration for precise biomarker determination

open access: yesInfoMat, EarlyView.
The multifunctional integration of MoS2 into the SERS platform addresses key limitations in accurate quantification. Atomically thin MoS2 reduces spot‐to‐spot variations via plasmonic calibration and improves quantification reliability by ensuring consistent signal changes with analyte concentration.
Seungkyun Lee   +9 more
wiley   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

open access: yesInterdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang   +6 more
wiley   +1 more source

[Prostate specific antigen].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990
E, Paus, L, Theodorsen
openaire   +1 more source

Diagnostic Efficiency of Age‐Adjusted PSAD for Prostate Cancer and Clinically Significant Prostate Cancer: Construction and Nomogram Validation

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Nomogram model performance: The study develops a predictive model using Lasso regression, incorporating key clinical factors, which achieves excellent discriminatory performance in both training and validation sets. Potential for clinical application: The A‐PSAD‐based model shows great promise for personalized PCa screening, particularly in reducing ...
Ziyang Liu   +6 more
wiley   +1 more source

Patient and Physician Perceptions of Prostate-Specific Antigen Testing Among Black Individuals.

open access: yesJAMA Netw Open
Lee JR   +16 more
europepmc   +1 more source

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