Results 91 to 100 of about 205,631 (301)

Renal-type clear cell carcinoma of prostate: A case report and review of literature

Indian Journal of Pathology and Microbiology, 2018
We analyzed the clinicopathological features of renal-type clear cell carcinoma (RTCCC) in the prostate and its diagnosis according to the example in our hospital and review of the literature.
Guangjie Liao, Xinke Zhang, Zhongjian Li, Su Lan, Miaoli Huang, Weijian Huang   +5 more
doaj   +1 more source

How to study basement membrane stiffness as a biophysical trigger in prostate cancer and other age-related pathologies or metabolic diseases [PDF]

, 2016
Here we describe a protocol that can be used to study the biophysical microenvironment related to increased thickness and stiffness of the basement membrane (BM) during age-related pathologies and metabolic disorders (e.g. cancer, diabetes, microvascular
Breit, Claudia, Clarke, Mitchell, Etchandy, Guillermina, Mohammad, Mohammad A., Pickwell, Sage, Rodriguez-Teja, Mercedes, Stasiuk, Graeme J., Sturge, Justin, Talar, Kamil, Wang, Kai   +9 more
core   +3 more sources

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li, Danyang Chen, Yongzhen Xia, Yili Long, Nan Huang, Rongna Li, Mengting Shi, Mairehaba Kadier, Huafeng Luo, Xiaohui Chen, Hao Liu, Guanmin Jiang   +11 more
wiley   +1 more source

Label-free isolation of prostate circulating tumor cells using Vortex microfluidic technology. [PDF]

, 2017
There has been increased interest in utilizing non-invasive "liquid biopsies" to identify biomarkers for cancer prognosis and monitoring, and to isolate genetic material that can predict response to targeted therapies. Circulating tumor cells (CTCs) have
Che, James, Di Carlo, Dino, Jeffrey, Stefanie S, Kulkarni, Rajan P, Lemaire, Clementine A, Liu, Haiyan E, Matsumoto, Melissa, Pao, Edward, Renier, Corinne, Rettig, Matthew, Sollier-Christen, Elodie, Srivinas, Sandy, Triboulet, Melanie   +12 more
core   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Renal cell carcinoma with local tumor extension and pulmonary tumor embolism captured on hybrid CT and F18-PSMA PET

Radiology Case Reports
A 52-year-old female presented to hospital with acute dyspnea on a background of renal cell carcinoma in remission. Initial CT imaging demonstrated a large volume of acute occlusive pulmonary emboli in segmental and subsegmental arteries.
Vincent Lam, MD, Adelle Thea, MD, Claire Cuscaden, FAANMS, FRANZCR, MBBS   +2 more
doaj   +1 more source

Optimal MRI sequences for 68Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer. [PDF]

, 2017
BackgroundPET/MRI can be used for the detection of disease in biochemical recurrence (BCR) patients imaged with 68Ga-PSMA-11 PET. This study was designed to determine the optimal MRI sequences to localize positive findings on 68Ga-PSMA-11 PET of patients
Behr, Spencer C, Carroll, Peter R, Greene, Kirsten L, Hope, Thomas A, Lake, Spencer T, Small, Eric J, Westphalen, Antonio C, Zagoria, Ronald   +7 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]

, 2013
Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di, Festuccia, Claudio, Gravina, Giovanni Luca, Mancini, Andrea, Marampon, Francesco, Pasquale, Boris Di, Ranieri, Guido, Ricevuto, Enrico   +7 more
core   +1 more source