Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Contemporary Management of Malignancies of the Parotid Gland: A State‐of‐the‐Art Review
Abstract Objectives To provide a systematic update on the contemporary management of malignancies of the parotid gland (MPG), focusing on evidence‐based practices and emerging therapeutics. Data Sources PubMed literature search. Review Methods A search protocol was designed according to the Preferred Reporting Items for Systematic Reviews and Meta ...
Anthony Tang +10 more
wiley +1 more source
A prostate-specific membrane antigen targeted small molecule-drug conjugate for efficient prostate cancer therapy at a low dosage. [PDF]
Zhang J +8 more
europepmc +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Prostate-specific membrane antigen targeted organic semiconducting polymer nanoparticles for enhanced photothermal therapy of prostate cancer. [PDF]
Jiang Z +8 more
europepmc +1 more source
ABSTRACT Introduction PSMA‐PET offers an opportunity to reduce the mischaracterization of disease in active surveillance (AS) and focal therapy (FT) candidates. We describe the results of a pilot clinical trial evaluating 18F‐radiohybrid(rh)PSMA‐7.3‐PET/MRI to detect occult adverse pathology among potential AS and FT candidates (NCT05852041).
Ridwan Alam +11 more
wiley +1 more source
Radio-guided lymph node resection with prostate-specific membrane antigen in prostate cancer: Initial experience. [PDF]
Gonzalez CC +10 more
europepmc +1 more source
ABSTRACT Background To compare choline PET‐CT and PSMA PET‐CT in a cohort of patients with high‐risk localized prostate cancer, assessing the diagnostic capacity of both tests. whose therapeutic approach could be modified based on the results. Methods An observational study was conducted in 116 patients with high‐risk prostate cancer between January ...
M. A. Tárraga‐Honrubia +5 more
wiley +1 more source
In the Era of mpMRI and PSMA PET/CT: Does Digital Rectal Examination Still Matter?
ABSTRACT Background With the increasing integration of multiparametric MRI (mpMRI) and 68Ga‐PSMA PET/CT into the diagnostic and staging algorithms of prostate cancer (PCa), digital rectal examination (DRE)—a once foundational and cost‐effective physical examination—has gradually become marginalized in daily clinical practice.
Anil Eker +10 more
wiley +1 more source
PSMA-RADS 2.0: clinical validation and technical considerations for prostate-specific membrane antigen positron emission tomography/computed tomography image interpretation. [PDF]
Cheng L +10 more
europepmc +1 more source

