ABSTRACT Pancreatic cancer, one of the most malignant solid tumors with the poorest prognosis, is commonly treated with gemcitabine (GEM)‐based systemic chemotherapy. However, chemoresistance remains a significant therapeutic challenge. Ferroptosis, a novel form of programmed cell death, has demonstrated exceptional susceptibility in chemoresistant ...
Jiaqiang Ren +10 more
wiley +1 more source
Prostate-Specific Membrane Antigen (PSMA)-Directed Dendrimer-Camptothecin Conjugate for Targeted Treatment of Prostate Cancer. [PDF]
Dhull A +8 more
europepmc +1 more source
Activatable smart contrast agents for photoacoustic imaging
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh +5 more
wiley +1 more source
Diagnostic value of 18 F-prostate-specific membrane antigen-1007 PET/MRI versus 18 F-prostate-specific membrane antigen-1007 PET/computed tomography for biochemical recurrence of prostate cancer after radical prostatectomy. [PDF]
Zeng Y, Liao H, Jiang G, Wu G, Zhong J.
europepmc +1 more source
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó +9 more
wiley +1 more source
Salvage radiotherapy with prostate-specific membrane antigen-directed focal boost: A precision approach for recurrent prostate cancer. [PDF]
Lan TL +8 more
europepmc +1 more source
Abstract Background Metastatic prostate cancer tumor seeding within a percutaneous biopsy tract is rare. While reports of tumor seeding following perineal and transrectal prostate biopsies exist, no cases of prostate cancer tumor seeding along a metastatic percutaneous bone biopsy tract detected by prostate specific membrane antigen (PSMA) positron ...
Thomas Neerhut +3 more
wiley +1 more source
Prodrugs Targeting Prostate-Specific Membrane Antigen against Prostate Cancer. [PDF]
Liolios C +3 more
europepmc +1 more source
Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors [PDF]
Achilefu, Samuel, et al,
core +1 more source
Advances in cholesterol and lipoproteins detection for healthcare: A review
Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta +7 more
wiley +1 more source

