Results 191 to 200 of about 1,482,586 (339)

Deep Docking: A Deep Learning Platform for Augmentation of Structure Based Drug Discovery

ACS Central Science, 2020
Francesco Gentile, Vibudh Agrawal, Michael Hsing, Anh-Tien Ton, Fuqiang Ban, Ulf Norinder, Martin E. Gleave, Artem Cherkasov   +7 more
doaj   +1 more source

The effect of opium consumption on prostate cancer among Iranian patients: A retrospective analytical study. [PDF]

Medicine (Baltimore)
Mohammadi R, Mirzaei M, Tajik Ghanbari A, Mirolyaie A, Abbasi M, Ranjbaran S.   +5 more
europepmc   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Correction to: Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells. [PDF]

Br J Cancer
Dixon KM, Lui GYL, Kovacevic Z, Zhang D, Yao M, Chen Z, Dong Q, Assinder SJ, Richardson DR.   +8 more
europepmc   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Retraction: NF-κB inhibition promotes apoptosis in androgen-independent prostate cancer cells by the photothermal effect via the IκBα/AR signaling pathway

, 2022
Chenfei Kong, Miao Hao, Xi Chen, Xiaoming Zhao, Yuqian Wang, Jing Li, Yiyao Gao, Hao Zhang, Yang Bai, Jinlan Jiang   +9 more
openalex   +2 more sources

Primary extranodal marginal zone non-hodgkin lymphoma of the prostate: a case report. [PDF]

Front Oncol
Gao X, Wang X, Wang X, Cai H.
europepmc   +1 more source

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu, Taiheng Ma, Qi Liu, He Zhu, Zheng Fang, Jiahong Ma, Ting Yu, Yan Wang, Jiahua Zhou, Xiaoyan Liu, Yaqian Li, Zhimou Guo, Xinmiao Liang, Mingming Dong, Deguang Sun, Mingliang Ye   +15 more
wiley   +1 more source

The relationship between immune cells and prostate cancer, and the mediating role of metabolites: a Mendelian randomization study [PDF]

Xipeng Wu, Wenda Zou, Ziwei Liu
openalex   +1 more source