Results 51 to 60 of about 1,247,684 (370)

Risk of second primary Cancer among bladder Cancer patients: a population-based cohort study in Korea

BMC Cancer, 2018
Background For the expanding population of bladder cancer survivors in Korea, the development of subsequent cancers is a significant concern. Here, we provide the second primary cancer incidence rates and types in Korean patients with bladder cancer ...
Whi-An Kwon, Jae Young Joung, Jiwon Lim, Chang-Mo Oh, Kyu-Won Jung, Sung Han Kim, Ho Kyung Seo, Weon Seo Park, Jinsoo Chung, Kang Hyun Lee, Young-Joo Won   +10 more
doaj   +1 more source

Comprehensive study of good model training for prostate segmentation in volumetric MRI [PDF]

arXiv, 2022
Prostate cancer was the third most common cancer in 2020 internationally, coming after breast cancer and lung cancer. Furthermore, in recent years prostate cancer has shown an increasing trend. According to clinical experience, if this problem is detected and treated early, there can be a high chance of survival for the patient.
arxiv  

Apalutamide Treatment and Metastasis‐free Survival in Prostate Cancer

New England Journal of Medicine, 2018
Background Apalutamide, a competitive inhibitor of the androgen receptor, is under development for the treatment of prostate cancer. We evaluated the efficacy of apalutamide in men with nonmetastatic castration‐resistant prostate cancer who were at high ...
Matthew R. Smith, F. Saad, S. Chowdhury, S. Oudard, B. Hadaschik, J. Graff, D. Olmos, P. Mainwaring, J. Lee, H. Uemura, A. Lopez-Gitlitz, G. Trudel, B. Espina, Y. Shu, Y. Park, W. Rackoff, Margaret K Yu, E. Small   +17 more
semanticscholar   +1 more source

Prostate Cancer Incidence and Survival, by Stage and Race/Ethnicity — United States, 2001–2017

MMWR. Morbidity and mortality weekly report, 2020
Among U.S. men, prostate cancer is the second leading cause of cancer-related death (1). Past studies documented decreasing incidence of prostate cancer overall since 2000 but increasing incidence of distant stage prostate cancer (i.e., signifying spread
D. Siegel, M. E. O’Neil, T. Richards, Nicole F. Dowling, H. Weir   +4 more
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal, Dario B. Rodrigues, Weiguang Yao, Jason K. Molitoris, Matthew E. Witek, Shifeng Chen   +5 more
wiley   +1 more source

Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer

Scientific Reports
FOXA1 is a pioneer transcription factor that is frequently mutated in prostate, breast, bladder, and salivary gland malignancies. Indeed, metastatic castration-resistant prostate cancer (mCRPC) commonly harbour FOXA1 mutations with a prevalence of 35 ...
Kevin J. Tam, Liangliang Liu, Michael Hsing, Kush Dalal, Daksh Thaper, Brian McConeghy, Parvin Yenki, Satyam Bhasin, James W. Peacock, Yuzhuo Wang, Artem Cherkasov, Paul S. Rennie, Martin E. Gleave, Christopher J. Ong   +13 more
doaj   +1 more source

Structure-Based Study to Overcome Cross-Reactivity of Novel Androgen Receptor Inhibitors

Cells, 2022
The mutation-driven transformation of clinical anti-androgen drugs into agonists of the human androgen receptor (AR) represents a major challenge for the treatment of prostate cancer patients. To address this challenge, we have developed a novel class of
Mariia Radaeva, Huifang Li, Eric LeBlanc, Kush Dalal, Fuqiang Ban, Fabrice Ciesielski, Bonny Chow, Helene Morin, Shannon Awrey, Kriti Singh, Paul S. Rennie, Nada Lallous, Artem Cherkasov   +12 more
doaj   +1 more source

Prostate Lesion Estimation using Prostate Masks from Biparametric MRI [PDF]

arXiv, 2023
Biparametric MRI has emerged as an alternative to multiparametric prostate MRI, which eliminates the need for the potential harms to the patient due to the contrast medium. One major issue with biparametric MRI is difficulty to detect clinically significant prostate cancer (csPCA).
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source