Results 161 to 170 of about 683,284 (269)

CDC7 is a targetable regulator of advanced prostate cancer. [PDF]

Sci Rep
Hartono AB, Hwang H, Paparaju S, Liu S, Brooks JD, Corey E, Stoyanova T.   +6 more
europepmc   +1 more source

Impact of Abdominal/Pelvic Surgery on Late Rectal Bleeding and Increased Stool Frequency/tenesmus After Prostate Cancer High-dose 3DCRT [PDF]

, 2007
V. Vavassori, R. Valdagni, T. Rancati, Gianni Fellin, C. Bianchí, Valeria Casanova Borca, G. Girelli, L. Menegotti, Santiago Nava, C. Fiorino   +9 more
openalex   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Prostate Cancer Screening: Evidence, Ethics, and Reframing Education. [PDF]

Am J Mens Health
Takahashi T.
europepmc   +1 more source

A dose finding clinical trial of cabozantinib (XL184) administered in combination with abiraterone acetate in metastatic castration‐resistant prostate cancer

, 2018
Atish D. Choudhury, Kathryn P. Gray, Jeffrey G. Supko, Lauren C. Harshman, Mary‐Ellen Taplin, Amanda F. Pace, Matthew S. Farina, Katherine Zukotynski, Brandon Bernard, Philip W. Kantoff, Mark M. Pomerantz, Christopher J. Sweeney   +11 more
openalex   +2 more sources

A Radiobiological Perspective between IMRT and 3D Conformal Treatment of Prostate Cancer [PDF]

, 2009
S Stathakis, C Buckey, Panayiotis Mavroidis, Gregory P. Swanson, N Papanikolaou, Michael T. Smith, D Giantsoudi, E. Dzintars   +7 more
openalex   +1 more source

Enzymatic Remodelling of Tumour Microenvironment Enhances Anti‐CEACAM5 CAR T‐Cell Efficacy Against Colorectal Cancer

Advanced Science, EarlyView.
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik, Christopher J. Ward, Soura Chakraborty, Ziwei Zhang, Daniel Heraghty, Prasanna Suresh, Bing Li, Shekhar Kedia, Jhuma Pramanik, Simon J. Davis, James P. Roy, Michael A. Chapman, Bidesh Mahata, David Klenerman   +13 more
wiley   +1 more source

Neoadjuvant Therapies for Prostate Cancer-Current Paradigms and Future Directions. [PDF]

Cancers (Basel)
Sandhu K, Al-Khanaty A, Hennes D, Chen D, Dinneen E, Delgado C, Lawrentschuk N, Eapen RS, Murphy DG, Perera M.   +9 more
europepmc   +1 more source

Synchronous bladder and prostate cancers in the specimens of radical cystoprostatectomy: A multicenter retrospective analysis

, 2014
Berat Cem Özgür, Ersin Köseoğlu, Ali İhsan Arık, Haşmet Sarıcı, Övünç Bilgin, Cem Nedim Yücetürk, Elif Özer, Eşref Oğuz Güven, Onur Telli, Ali Atan, Muzaffer Eroğlu   +10 more
openalex   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source