Prostate-Specific Membrane Antigen-Based Therapeutics [PDF]
Advances in Urology, 2012 Prostate cancer (PC) is the most common noncutaneous malignancy affecting men in the US, leading to significant morbidity and mortality. While significant therapeutic advances have been made, available systemic therapeutic options are lacking.
Naveed H. Akhtar +4 more
doaj +6 more sources
Updates of prostate cancer staging: Prostate-specific membrane antigen [PDF]
Investigative and Clinical Urology, 2016 The ability to accurately stage prostate cancer in both the primary and secondary staging setting can have a major impact on management. Until recently radiological staging has relied on computer tomography, magnetic resonance imaging, and nuclear bone
Niranjan J Sathianathen +7 more
doaj +4 more sources
Co-expression and impact of prostate specific membrane antigen and prostate specific antigen in prostatic pathologies [PDF]
Journal of Experimental & Clinical Cancer Research, 2010 Background The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role ...
Nouira Yassin +8 more
doaj +3 more sources
Prostate-specific membrane antigen-mediated theragnostics in prostate cancer [PDF]
Investigative and Clinical Urology, 2021 Seung-hwan Jeong, Cheol Kwak
doaj +3 more sources
Prostate-Specific Membrane Antigen–Guided Surgery [PDF]
Journal of Nuclear Medicine, 2019 Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)-ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined.
Maurer, T. +7 more
openaire +4 more sources
Substrate specificity of prostate-specific membrane antigen [PDF]
Bioorganic & Medicinal Chemistry, 2007 A series of putative dipeptide substrates of prostate-specific membrane antigen (PSMA) was prepared that explored alpha- and beta/gamma-linked acidic residues at the P1 position and various chromophores at the P2 position, while keeping the P1' residue constant as L-Glu.
Anderson, Marc O +6 more
openaire +3 more sources
Pulmonary tumor embolism in renal cell carcinoma detected by hybrid CT and F18-PSMA PET
Radiology Case Reports, 2023 We present the case of a 75-year-old female in which a pulmonary tumor embolism was detected incidentally on a prostate-specific membrane antigen positron emission tomography-computed tomography restaging scan.
Jared E. Tan, B-BMED +2 more
doaj +1 more source
The effects of specific expression of apoptin under the control of PSES and PSA promoter on cell death and apoptosis of LNCaP cells [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Apoptotic effect of apoptin has been demonstrated in numerous studies. However, its tumor specificity has been questioned by some reports.
Vida Mohammadi +6 more
doaj +1 more source
European Urology Open Science, 2021 Initial reports of a clinical response in patients treated with the radioligand [177Lu]-PSMA-617 for castration-resistant prostate cancer (CRPC) are promising, despite known inter- and intrapatient heterogeneity.
Judith Stangl-Kremser +17 more
doaj +1 more source
Optimization of PET protocol and interrater reliability of 18F-PSMA-11 imaging of prostate cancer [PDF]
, 2020 Background Several scan parameters for PET imaging with F-18-PSMA-11 such as dosage, acquisition time and scan duration were evaluated to determine the most appropriate scan protocol, as well as the effect of furosemide administration on lesion ...
Achten, Eric +7 more
core +2 more sources