A recent study proposed a system of unfavourable and favourable histology categories to risk‐stratify prostate cancer patients. In a study of radical prostatectomy cases which had Decipher molecular classifier testing, unfavourable histology was associated with higher Decipher scores, increased biochemical recurrence (BCR) risk and improved BCR ...
Nancy Y Greenland +9 more
wiley +1 more source
Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano +6 more
wiley +1 more source
Post-Prostatectomy Target-Normal Structure Overlap Volumes using Computed Tomography and Radioimmunoscintigraphy Images for Radiotherapy Treatment Planning [PDF]
Ashesh B. Jani +4 more
openalex +1 more source
Abstract Prostate cancer (PCa) lacks reliable and accurate tissue‐based biomarkers to support prognostic stratification and clinical treatment decisions. Current diagnostic assessment, including Gleason grading, has limitations such as interobserver variability and insufficient granularity for disease aggressiveness. Fibroblast activation protein (FAP)
Jenni Säilä +5 more
wiley +1 more source
MP87-04 NATIONAL TRENDS IN UTILIZATION OF SURGICAL THERAPIES FOR POST-PROSTATECTOMY STRESS URINARY INCONTINENCE [PDF]
Yahir Santiago‐Lastra +2 more
openalex +1 more source
Abstract The aim of this study was to evaluate the predictive value of homologous recombination deficiency scores for therapeutic efficacy in prostate cancer across various disease stages under different regimens. We collected tissue samples from 167 prostate cancer patients and performed genomic sequencing to assess homologous recombination deficiency
Qiyu Zhu +11 more
wiley +1 more source
1038: Relationship Between Cystograpidcally-Detected Urinary Extravasation and Urinary Continence Following Laparoscopic Radical Prostatectomy [PDF]
Mark L. Gonzalgo +4 more
openalex +1 more source
Direct Comparison of Low-Dose-Rate Brachytherapy Versus Radical Prostatectomy Using the Surgical Definition of Biochemical Recurrence for Patients with Intermediate-Risk Prostate Cancer [PDF]
Hideyasu Tsumura +11 more
openalex +1 more source
Abstract Purpose This study evaluated the impact of a commercial AI‐assisted contouring tool on intra‐ and inter‐observer variability in prostate radiation therapy and assessed the dosimetric consequences of geometric contour differences. Methods Two experienced radiation oncologists independently delineated clinical target volume (CTV) and organs at ...
Najmeh Arjmandi +5 more
wiley +1 more source
Effects of Thienopyridine Class Antiplatelets on Bleeding Outcomes Following Robot-Assisted Radical Prostatectomy [PDF]
Masashi Kubota +33 more
openalex +1 more source

