Results 121 to 130 of about 86,828 (245)

Correlation of unfavourable and favourable histology at radical prostatectomy with Decipher scores and freedom from biochemical recurrence

open access: yesHistopathology, Volume 88, Issue 3, Page 605-614, February 2026.
A recent study proposed a system of unfavourable and favourable histology categories to risk‐stratify prostate cancer patients. In a study of radical prostatectomy cases which had Decipher molecular classifier testing, unfavourable histology was associated with higher Decipher scores, increased biochemical recurrence (BCR) risk and improved BCR ...
Nancy Y Greenland   +9 more
wiley   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano   +6 more
wiley   +1 more source

Validation of fibroblast activation protein and α‐smooth muscle actin as prognostic biomarkers in prostate cancer through AI‐assisted image analysis of dual‐marker IHC

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Prostate cancer (PCa) lacks reliable and accurate tissue‐based biomarkers to support prognostic stratification and clinical treatment decisions. Current diagnostic assessment, including Gleason grading, has limitations such as interobserver variability and insufficient granularity for disease aggressiveness. Fibroblast activation protein (FAP)
Jenni Säilä   +5 more
wiley   +1 more source

Assessing the association between homologous recombination deficiency scores and treatment response in localized and metastatic prostate cancer

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract The aim of this study was to evaluate the predictive value of homologous recombination deficiency scores for therapeutic efficacy in prostate cancer across various disease stages under different regimens. We collected tissue samples from 167 prostate cancer patients and performed genomic sequencing to assess homologous recombination deficiency
Qiyu Zhu   +11 more
wiley   +1 more source

Direct Comparison of Low-Dose-Rate Brachytherapy Versus Radical Prostatectomy Using the Surgical Definition of Biochemical Recurrence for Patients with Intermediate-Risk Prostate Cancer [PDF]

open access: green, 2022
Hideyasu Tsumura   +11 more
openalex   +1 more source

Clinical validation of AI‐assisted contouring in prostate radiation therapy treatment planning: Highlighting automation bias and the need for standardized quality assurance

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Purpose This study evaluated the impact of a commercial AI‐assisted contouring tool on intra‐ and inter‐observer variability in prostate radiation therapy and assessed the dosimetric consequences of geometric contour differences. Methods Two experienced radiation oncologists independently delineated clinical target volume (CTV) and organs at ...
Najmeh Arjmandi   +5 more
wiley   +1 more source

Effects of Thienopyridine Class Antiplatelets on Bleeding Outcomes Following Robot-Assisted Radical Prostatectomy [PDF]

open access: green, 2023
Masashi Kubota   +33 more
openalex   +1 more source

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