Results 131 to 140 of about 86,828 (245)

Effect of tranexamic acid irrigation on perioperative blood loss during mini‐percutaneous nephrolithotomy: A pilot double‐blind randomised controlled trial

open access: yesBJUI Compass, Volume 7, Issue 1, January 2026.
Abstract Objective To evaluate the efficacy and safety of adding 0.1% tranexamic acid (TXA) to irrigation fluid in reducing perioperative blood loss during mini‐percutaneous nephrolithotomy (mini‐PCNL). Patients and Methods In this prospective, randomised study, 40 patients undergoing mini‐PCNL were allocated to receive irrigation fluid containing ...
Ornnicha Prohsoontorn   +6 more
wiley   +1 more source

Effects of Prior Local Therapy by Radical Prostatectomy or Radiotherapy on the Efficacy and Quality of Life of Patients Treated With Darolutamide in ARAMIS

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Darolutamide plus androgen‐deprivation therapy (ADT) improved metastasis‐free survival (MFS) by 2 years and reduced the risk of death by 31% in nonmetastatic castration‐resistant prostate cancer (nmCRPC) in ARAMIS. Prior local therapy may influence the efficacy of subsequent systemic therapy.
Matthias Saar   +18 more
wiley   +1 more source

Adherence to Guidelines among Italian Urologists on Imaging Preoperative Staging of Low-Risk Prostate Cancer: Results from the MIRROR (Multicenter Italian Report on Radical Prostatectomy Outcomes and Research) Study [PDF]

open access: gold, 2012
Alchiede Simonato   +10 more
openalex   +1 more source

Emergence of BRCA Reversion Mutations in Prostate Cancer Prior to PARP Inhibitor Exposure: Clinical and Therapeutic Implications

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Inactivating BRCA1/2 mutations confer sensitivity to poly(ADP‐ribose) polymerase inhibitors (PARPi) in prostate cancer (PCA). However, secondary BRCA1/2 reversion mutations (BRCArev) can restore BRCA function and mediate acquired PARPi resistance.
Douglas I. Lin   +11 more
wiley   +1 more source

Theranostic Nanoparticles in Prostate Cancer: Disrupting Hypoxia‐Induced Glycolysis by Targeting Hypoxia‐Inducible Factor‐1 Alpha and Downstream Metabolites

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
The debate in the field of cancer immunotherapy is being changed as nanotechnology breaks the obstacle of cancer immune evasion, target delivery, and systemic toxicity. Esthetically advanced methods that are discussed in this review are nanovaccine, nanoparticle‐enabled checkpoint barrier, cytokine delivery, and T‐cell modulation techniques that ...
Daniel Ejim Uti   +7 more
wiley   +1 more source

Management of a Large Bone Impaction in the Esophagus With Cola and Catheters: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Graphical abstract illustrating cola‑assisted management of distal esophageal bone impaction: initial normal cardiothoracic workup, failed standard endoscopic retrieval, endoscopic cola infusion to soften the impacted bolus, and uneventful recovery with complete mucosal healing at 3‑month follow‑up.
Negar Ghasemloo   +8 more
wiley   +1 more source

Robotic assisted radical prostatectomy improves biochemical recurrence-free survival: The PROCA-life study. [PDF]

open access: yesJ Robot Surg
Knutsen T   +8 more
europepmc   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima   +15 more
wiley   +1 more source

Impact of a robotic-assisted transperineal biopsy platform on pathologic upgrading and downgrading at prostatectomy. [PDF]

open access: yesWorld J Urol
Alargkof V   +9 more
europepmc   +1 more source

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