TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Combined robot-assisted surgery of upper and lower genitourinary tract with excellent early functional and oncological outcome - a case report of a concomitant nerve-sparing radical prostatectomy, diverticulectomy and ureterectomy. [PDF]
Lüdecke J +6 more
europepmc +1 more source
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
The Role of Robot-Assisted Radical Prostatectomy in the Management of Prostate Cancer and Future Perspectives. [PDF]
Rinaldi M +4 more
europepmc +1 more source
Deep vein thrombosis and prostatectomy [PDF]
Keith N. Van Arsdalen +4 more
openalex +1 more source
Evaluation of a prostate SBRT planning workflow using auto‐segmentation and knowledge‐based planning
Abstract Purpose This study investigates a prostate stereotactic body radiotherapy (SBRT) planning workflow integrating commercial artificial intelligence (AI) contouring and knowledge‐based planning (KBP). The purpose is to determine whether AI‐generated contours are comparable to physician‐delineated contours in achieving dosimetric goals. Methods In
Trisha Jones +7 more
wiley +1 more source
The PSMA-PET Conundrum: A Survey of UK Prostate Cancer Surgeons and Their Use of PSMA-PET Prior to Radical Prostatectomy. [PDF]
Karanjia RN +3 more
europepmc +1 more source
THE APPLICATION OF A COMPUTER SORTING PROGRAM TO PROSTATECTOMY PATIENTS
D.W. HILL, R. I. Bodman
openalex +1 more source

