Results 211 to 220 of about 208,651 (377)

Role of Cell‐Cycle Proliferation Test, Triple Hit Phenotype, and TMPRSS2‐ERG Expression to Evaluate the Risk of Progression in Prostate Cancer Patients Under Active Surveillance

open access: yesThe Prostate, Volume 85, Issue 12, Page 1104-1113, September 2025.
ABSTRACT Background An accurate estimation of progression risk in patients with prostate cancer (PCa) amenable to active surveillance (AS) is still an unmet need. Among available biomarkers, we considered Prolaris cell‐cycle progression (CCP) test, “triple hit” phenotype (ERG overexpression, PTEN and prostein expression loss) and elevated expression ...
Marco Oderda   +14 more
wiley   +1 more source

Genomic Signatures Correlating With Adverse Pathologic Features in Men Eligible for Active Surveillance

open access: yesThe Prostate, Volume 85, Issue 12, Page 1114-1120, September 2025.
ABSTRACT Background Genomic biomarkers offer opportunities to improve risk stratification for patients with prostate cancer. We performed a transcriptomic profile of active surveillance (AS)‐eligible patients who underwent radical prostatectomy (RP) to understand genomic associations with adverse pathologic features (APF) at RP.
Jamie Michael   +12 more
wiley   +1 more source

Late Bowel Symptoms in Long‐Term Survivors of Prostate Cancer Following Radiotherapy

open access: yesThe Prostate, Volume 85, Issue 13, Page 1181-1188, September 15, 2025.
ABSTRACT Background Despite advances in radiotherapy planning, some long‐term prostate cancer survivors experience persistent symptoms. Although overall quality of life appears comparable between patients treated with definitive and salvage radiotherapy and aligns with normative data, prostate‐specific deficits—particularly bowel symptoms—may persist ...
Isabella Gruber   +2 more
wiley   +1 more source

PRMT5:MEP50 Are Mediators of Treatment‐Induced Neuroendocrine Differentiation in Prostate Cancer

open access: yesThe Prostate, Volume 85, Issue 13, Page 1196-1207, September 15, 2025.
ABSTRACT Background Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer responsible for an estimated 20%–30% of castration‐resistant prostate cancer (CRPC) deaths. While NEPC can arise spontaneously, the majority of these cases emerge as treatment‐induced NEPC (tNEPC).
Hye Seung Nam   +7 more
wiley   +1 more source

A population-based analyses of the evolving management of cN1M0 prostate cancer in the PSMA-PET era. [PDF]

open access: yesBJUI Compass
Ward J   +18 more
europepmc   +1 more source

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