Results 61 to 70 of about 52,757 (299)

Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle. [PDF]

, 2012
The transcription factors Elk1 and serum response factor (SRF) are central regulators of cell cycle and phenotype in various cell types. Elk1 is activated by phosphorylation (serine-383), while activation of SRF requires its co-factor, myocardin ...
Christian G Stief, Strittmatter, Frank, Martin Hennenberg, Waidelich, Raphaela, Beckmann, Christer, Füllhase, Claudius, Rutz, Beata, Montorsi, Francesco, Petter Hedlund, Christer Beckmann, Christian Gratzke, Stief, Christian Georg, Raphaela Waidelich, Hedlund, Petter, Frank Strittmatter, Karl-Erik Andersson, Andersson, Karl-Erik, Francesco Montorsi, Hennenberg, Martin, Gratzke, Christian, Beata Rutz, Claudius Füllhase   +21 more
core   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Iron death and benign prostatic hyperplasia [PDF]

, 2023
Iron death and benign prostatic ...
zechao Zhang (9504245)
core   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

Emphasis on the management of embedded capsular hyperplasia nodules associated with benign prostatic hyperplasia

Current Urology
. Benign prostatic hyperplasia is commonly observed in older men, and surgery is the primary treatment. Management of prostatic hyperplasia nodules, especially embedded capsular hyperplasia nodules, is crucial for reducing the incidence of postoperative ...
Chenghao Zheng, Yiping Zhu, Yifeng Jing, Shujie Xia   +3 more
doaj   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Ultrasound‐Guided Transperineal Versus Transrectal Prostate Aspiration Biopsy in Diagnosing Prostate Cancer

Journal of Ultrasound in Medicine, EarlyView.
Background Ultrasound‐guided prostate biopsy is the standard method for the diagnosis of prostate cancer. However, the effect of the optimal puncture approach on diagnostic yield and patient outcomes remains controversial. Objective To compare the diagnostic effectiveness and clinical outcomes of ultrasound‐guided transperineal versus transrectal ...
Yue Cao, Hong Zhu, Junwei Wu
wiley   +1 more source

Correlation between Prostatic Calculi and Benign Prostatic Hyperplasia [PDF]

, 2021
Prostatic calculus is a common disease of the urinary system, Prostate stones are more common in middle-aged and elderly men, With the development of ultrasonic diagnosis, more and more patients with prostate stone were found in physical examination ...
Xiao, Chuan, Tang, Ruipeng
core  

Waist circumference is an independent risk factor for prostatic hyperplasia in Taiwanese males

Asian Journal of Surgery, 2011
Purpose: Benign prostatic hyperplasia is a common disease affecting older males. As obesity becomes an increasing problem worldwide, its role in prostatic hypertrophy has been discussed recently.
Hsu-Han Wang, Chi-Jeng Hsieh, Kuo-Jen Lin, Sheng-Hsien Chu, Cheng-Keng Chuang, Hsiao-Wen Chen, Min-Li Hsieh, Ta-Min Wang, Yu Chen, Kuan-Lin Liu, Hsin-Chien Huang, Yu-Chao Hsu, Yang-Jen Chiang   +12 more
doaj   +1 more source

Terazosin Attenuates Neuronal Pyroptosis by Regulating the Mitochondrial ROS/NLRP3 Inflammasome Axis Through Mitophagy in Cerebral Ischemia–Reperfusion Injury

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Cerebral ischemia–reperfusion injury (CI/RI) is a major cause of secondary neuronal damage following ischemic stroke. This study investigated whether terazosin (TZ) exerts neuroprotective effects by regulating mitophagy and the reactive oxygen species (ROS)/NOD‐like receptor protein 3 (NLRP3) inflammasome axis.
Wei Wang, Xin‐Yue Han, Li‐An Huang, Yu‐Sheng Zhang, Heng Meng, An‐Ding Xu   +5 more
wiley   +1 more source