Results 1 to 10 of about 15,775 (215)

Interobserver Variability in the Diagnosis of High-Grade Prostatic Intraepithelial Neoplasia in a Tertiary Hospital in Northern Jordan [PDF]

Clinical Pathology, 2020
Prostate intraepithelial neoplasia is described as a precursor lesion to prostatic adenocarcinoma. High-grade prostate intraepithelial neoplasia (HGPIN) is classified as both grade 2 and 3 prostate intraepithelial neoplasia due to inconsistency between ...
Najla Aldaoud, Amer Hallak, Nour Abdo, Samir Al Bashir, Noor Marji, Ashley Graboski-Bauer   +5 more
doaj   +2 more sources

The impact of metformin use on the risk of prostate cancer after prostate biopsy in patients with high grade intraepithelial neoplasia [PDF]

International Brazilian Journal of Urology, 2018
Purpose We report our experience on metformin use in diabetic patients and its impact on prostate cancer (PCa) after a high-grade prostatic intraepithelial neoplasia (HGPIN) diagnosis.
Lucio Dell'Atti, Andrea B. Galosi
doaj   +2 more sources

High-grade prostatic intraepithelial neoplasia. [PDF]

Korean J Urol, 2012
High-grade prostatic intraepithelial neoplasia (HGPIN) has been established as a precursor to prostatic adenocarcinoma. HGPIN shares many morphological, genetic, and molecular signatures with prostate cancer. Its predictive value for the development of future adenocarcinoma during the prostate-specific antigen screening era has decreased, mostly owing ...
Klink JC, Miocinovic R, Magi Galluzzi C, Klein EA.   +3 more
europepmc   +4 more sources

ERG expression in prostate cancer biopsies with and without high-grade prostatic intraepithelial neoplasia: a study in Jordanian Arab patients [PDF]

Research and Reports in Urology, 2019
Najla Aldaoud,1,2 Ashley Graboski-Bauer,3 Nour Abdo,4 Samir Al Bashir,1,2 Ashraf O Oweis,5 Hanadi Ebwaini,1 Yousef Hasen,1–2,6 Rami Alazab,7 Kiril Trpkov81Department of Pathology and Microbiology, King Abdullah University Hospital, Irbid, Jordan ...
Aldaoud N, Graboski-Bauer A, Abdo N, Al Bashir S, Oweis AO, Ebwaini H, Hasen Y, Alazab R, Trpkov K   +8 more
doaj   +2 more sources

Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer [PDF]

BMC Cancer, 2006
Background Molecular markers identifying alterations in proliferation and apoptotic pathways could be particularly important in characterizing high-risk normal or pre-neoplastic tissue. We evaluated the following markers: Ki67, Minichromosome Maintenance
Yang Ximing J, Deaton Ryan J, Ananthanarayanan Vijayalakshmi, Pins Michael R, Gann Peter H   +4 more
doaj   +4 more sources

Prostate biopsies containing prostate intraepithelial neoplasia and atypical small acinar proliferation: what to do? [PDF]

Einstein (São Paulo), 2009
Objective: The aim of the study was to assess the frequency of high-grade prostate intraepithelial neoplasia and atypical small acinar proliferations on a contemporary series, and their relation to posterior diagnosis of prostate cancer.
Fernando Korkes, Suellen Ka Gi Mo, Cristiane Sayuri Koza de Jesus, Marilia Germanos Castro   +3 more
doaj   +1 more source

Deletion of NKX3.1 via CRISPR/Cas9 Induces Prostatic Intraepithelial Neoplasia in C57BL/6 Mice [PDF]

Technology in Cancer Research & Treatment, 2020
Several techniques have been employed for deletion of the NKX3.1 gene, resulting in developmental defects of the prostate, including alterations in ductal branching morphogenesis and prostatic secretions as well as epithelial hyperplasia and dysplasia ...
Jin Ju Park MS, Ji Eun Kim PhD, Yoon Jeon PhD, Mi Rim Lee MS, Jun Young Choi MS, Bo Ram Song MS, Ji Won Park MS, Mi Ju Kang MS, Hyeon Jun Choi MS, Su Ji Bae MS, Ho Lee PhD, Byeong Cheol Kang PhD, Dae Youn Hwang PhD   +12 more
doaj   +2 more sources

Prostatic intraepithelial neoplasia-like ductal prostatic adenocarcinoma: A case suitable for active surveillance?

Urology Annals, 2017
In contrast to typical prostatic ductal adenocarcinoma, prostatic intraepithelial neoplasia (PIN)-like ductal adenocarcinoma is a rare variant of prostate cancer with low-grade clinical behavior.
Soroush Rais-Bahrami, Melissa R Dillard, Grace G Zhu, Jennifer B Gordetsky   +3 more
doaj   +2 more sources

Basal cell hyperplasia (BCH) versus high grade prostatic intraepithelial neoplasia (HGPIN) in tiny prostatic needle biopsies: Unusual diagnostic dilemma

Journal of the Egyptian National Cancer Institute, 2014
Background: Histopathological differentiation between BCH and HGPIN in prostatic needle biopsies is a diagnostic challenge. The gold standard for detection of HGPIN and BCH is histopathological examination; however subjectivity in interpretation and tiny
Fatma El-Zahraa Salah El-Deen Yassin, Eman M.S. Muhammad, Mohammed Zaki, Mohammed Dyaa Saleem, Rabab Ahmed Ahmed Mohammed   +4 more
doaj   +2 more sources

Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice. [PDF]

PLoS One, 2013
ELL-associated factor 2 (EAF2) is an androgen-responsive tumor suppressor frequently deleted in advanced prostate cancer that functions as a transcription elongation factor of RNA Pol II through interaction with the ELL family proteins.
Pascal LE, Ai J, Masoodi KZ, Wang Y, Wang D, Eisermann K, Rigatti LH, O'Malley KJ, Ma HM, Wang X, Dar JA, Parwani AV, Simons BW, Ittman MM, Li L, Davies BJ, Wang Z.   +16 more
europepmc   +6 more sources