Results 71 to 80 of about 15,814 (254)
ABSTRACT Objective Women diagnosed with ductal carcinoma in situ (DCIS) and clinicians have reported challenges in communication about DCIS, contributing to women's confusion and anxiety. This study explored how to improve communication about DCIS including alternative labels, language and other strategies.
Suzanna Apostolovski +3 more
wiley +1 more source
Background: Prediction of biological behavior in patients of prostate cancer (CaP) is a major challenge as current parameters only partially meet the need for prognostication.
Anju Bansal, Anup Gupta, Sunita Saxena
doaj +1 more source
Cancer prevention by targeting angiogenesis [PDF]
Healthy individuals can harbour microscopic tumours and dysplastic foci in different organs in an undetectable and asymptomatic state for many years. These lesions do not progress in the absence of angiogenesis or inflammation.
Albini A +4 more
core +1 more source
Abstract Background Although Black men experience earlier onset and higher mortality from prostate cancer (PCa), no studies to date have tested interventions that encourage adoption of risk‐adapted prostate‐specific antigen (PSA) screening. The authors conducted a 15‐month trial in clinics serving Chicago communities with high PCa mortality and Black ...
Peter H. Gann +10 more
wiley +1 more source
Prostatic stromal microenvironment and experimental diabetes
The diabetes causes alterations in various organ systems, including the male accessory sex glands. The prostate is very important in the reproductive process and it is a frequent target of malignant changes.
DL Ribeiro +5 more
doaj +1 more source
Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice. [PDF]
LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines.
Aurélien J C Pommier +11 more
doaj +1 more source
ABSTRACT Background and Aims The therapeutic limitations of conventional cancer treatment currently deployed are driving the development and creation of new nano‐drugs. Prostate cancer (PCa) is a prevalent clinical problem in older men with a significant global incidence, with 1.5 million cases reported in 2022.
Russell B. O. Ouma +2 more
wiley +1 more source
Cyclooxygenase-2 (COX-2): a molecular target in prostate cancer [PDF]
[Abstract] Epidemiological studies provided the first evidence that COX may be involved in the pathogenesis of cancer. In the process of carcinogenesis and in the route of intracellular signalling during carcinogenesis, COX-2 expression may be a ...
Antón-Aparicio, Luis M. +5 more
core +2 more sources
Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song +10 more
wiley +1 more source
Prostatic Intraepithelial Neoplasia in Genetically Engineered Mice [PDF]
Several mouse models of human prostate cancer were studied to identify and characterize potential precursor lesions containing foci of atypical epithelial cells. These lesions exhibit a sequence of changes suggesting progressive evolution toward malignancy.
Jae-Hak, Park +6 more
openaire +2 more sources

