Results 81 to 90 of about 15,890 (255)

Evaluation of immunoexpression and MDR1 promoter methylation levels in prostatic tissue samples [PDF]

, 2008
Os objectivos deste estudo foram: (1) Determinar os níveis de metilação do promotor do MDR1 em tecido prostático com adenocarcinoma (CaP), neoplasia intraepitelial prostática de alto grau (HGPIN), hiperplasia benigna (BPH) e tecido morfologicamente ...
Costa, Vera L., Henrique, Rui, Jerónimo, Carmen, Moura, Inês, Pais, Irene, Ribeiro, Franclim R.   +5 more
core  

Autocrine regulation of human prostate carcinoma cell proliferation by somatostatin through the modulation of the SH2 domain containing protein tyrosine phosphatase (SHP)-1 [PDF]

, 2002
The present study was intended to gain additional information on the growth regulation of prostate by somatostatin\ud (SRIF) and the intracellular events involved.
Angulo, Javier, Buscail, Louis, Colás Escudero, Begoña, Lopez, José Ignacio, López Ruiz, María del Pilar, Martín Orozco, Rosa María, Prieto Villapún, Juan Carlos, Ropero, Rosa María, Susini, Christiane, Valencia Torralba, Ana Montserrat, Zapata, Pedro Darío   +10 more
core   +3 more sources

The influence of age and the presence of prostate cancer on prostate volume, PSA and PSA density

BJU International, Volume 137, Issue 5, Page 805-812, May 2026.
Objective To assess prostate volume (PV) changes with age in symptomatic and asymptomatic men with and without clinically significant prostate cancer (csPCa). In symptomatic patients, we additionally analysed the effect of age and csPCa on PSA and PSA‐density (PSA‐D) and compared these to current National Institute for Health and Care Excellence (NICE)
Jill Rusbridge, Iztok Caglic, Liness Thavaraja, Nikita Sushentsev, Tristan Barrett   +4 more
wiley   +1 more source

Supplementation of polyunsaturated fatty acids (PUFAs) and aerobic exercise improve functioning, morphology, and redox balance in prostate obese rats

Scientific Reports, 2021
The high-fat diet (HFD) stimulates an increase in lipids and can be prejudicial for harmful to prostatic morphogenesis. Polyunsaturated fatty acid (PUFAs) have anti-inflammatory and antioxidant action in some types of cancer.
Allice Santos Cruz Veras, Rayana Loch Gomes, Maria Eduarda Almeida Tavares, Inês Cristina Giometti, Ana Paula Mattoso Miskulin Cardoso, Beatriz da Costa Aguiar Alves, Sabrina Alves Lenquiste, Luiz Carlos Marques Vanderlei, Giovana Rampazzo Teixeira   +8 more
doaj   +1 more source

Heat shock protein 90 is associated with hyperplasia and neoplastic transformation of canine prostatic epithelial cells [PDF]

, 2014
Heat shock protein 90 (HSP90) is a molecular chaperone that regulates critical signalling proteins of cancer development and progression. Abnormal levels of HSP90 have been observed in human prostatic carcinoma (PC), with prognostic and therapeutic ...
Benazzi, C., Della Salda, L., Mancini, M., Palmieri, C.   +3 more
core   +1 more source

The PRAGMATIC pathway ‐ PRostate cancer diAGnosis and MAnagement Triage In Clinical care

BJU International, Volume 137, Issue 5, Page 849-857, May 2026.
Objectives To investigate whether nurse navigator‐led triaging of high‐risk patients may reduce prostate cancer (PCa) diagnosis and treatment times using an in‐house bespoke PRostate cancer diAGnosis and MAnagement Triage In the Clinial care pathway (PRAGMATIC) triaging system, as locally advanced/metastatic disease should be diagnosed and treated ...
Abhishek Sharma, Teresa Campbell, Sagar Kanabar, Hannah Soanes, Ganesh Sathanapally, Anthony Bates, Rincy John, Charlotte Adams, Aisling Brassill, Bryony Lennon, Sanjay Sinha, Louise Flaxman, Vanessa von Hasseln, Philip Camilleri, Ami Sabharwal, Philip Charlton, Gerard Andrade, Mark Tuthill, Andrew Protheroe, Alastair D. Lamb, Tom Leslie, Aaron Leiblich, Francisco Lopez, Clare Verrill, Fergus Gleeson, Ruth MacPherson, Freddie C. Hamdy, Richard Bell, Richard J. Bryant   +28 more
wiley   +1 more source

Unsuspected Prostate Cancer After Cystoprostatectomy: A Comparison Between Two Periods in Taiwan

Journal of the Formosan Medical Association, 2009
The incidence of and mortality rate from prostate cancer have been rising rapidly in Taiwan in recent years. Prostate specimens obtained during cystoprostatectomy may play a role in the study of prostate cancer evolution.
Jian-Ri Li, Chi-Rei Yang, John Wang, Yen-Chuan Ou, Hao-Chung Ho, Chen-Li Cheng   +5 more
doaj   +1 more source

Spatial omics for profiling the dynamic tumor microenvironment

Clinical &Translational Immunology, Volume 15, Issue 4, 2026.
Spatially resolved transcriptomics and proteomics map RNA/protein in intact tumor tissues, revealing crucial cancer–immune interactions across the different stages of tumor evolution. Integrating AI promises translational impact, but gaps in cross‐platform integration, standards, compute, validation and interpretability remain.
Hao Nguyen, Merrin Mary Eapen, Quan Nguyen, Ankur Sharma   +3 more
wiley   +1 more source

Roles of tumor suppressors in regulating tumor-associated inflammation. [PDF]

, 2014
Loss or silencing of tumor suppressors (TSs) promotes neoplastic transformation and malignant progression. To date, most work on TS has focused on their cell autonomous effects.
Karin, M, Yang, L
core   +1 more source

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression

Molecular Carcinogenesis, Volume 65, Issue 4, Page 508-522, April 2026.
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Rachel Clark, Achinto Saha, G. Lavender Hackman, Chelsea A. Friedman, Ruggiero Gorgoglione, Stefano Tiziani, John DiGiovanni   +6 more
wiley   +1 more source