Results 71 to 80 of about 15,890 (255)

Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

open access: yesBJU International, EarlyView.
Objectives To evaluate the feasibility and diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland) for the assessment of penile cancer (PeCa) specimens, and to compare FCM‐based diagnoses with standard formalin‐fixed, paraffin‐embedded (FFPE) histopathology ...
Xiaohu Zhang   +8 more
wiley   +1 more source

Prostatic stromal microenvironment and experimental diabetes

open access: yesEuropean Journal of Histochemistry, 2009
The diabetes causes alterations in various organ systems, including the male accessory sex glands. The prostate is very important in the reproductive process and it is a frequent target of malignant changes.
DL Ribeiro   +5 more
doaj   +1 more source

Building a Robust Investigator‐Initiated Platform: The I‐CARE Experience

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1537-1546, June 2026.
Investigator‐initiated studies that include information collected by patients are rising, but limited data is available on patient and investigator experience in this setting. The I‐CARE cohort included patients with inflammatory bowel disease (IBD) monthly collecting clinical information in 15 countries for up to 6 years.
Julien Kirchgesner   +906 more
wiley   +1 more source

Correlation of p53 immunoexpression with DNA ploidy and apoptotic index in subsets of prostate cancer: A marker reiterated in progression and recurrence of prostate cancer

open access: yesSouth Asian Journal of Cancer, 2015
Background: Prediction of biological behavior in patients of prostate cancer (CaP) is a major challenge as current parameters only partially meet the need for prognostication.
Anju Bansal, Anup Gupta, Sunita Saxena
doaj   +1 more source

Liver x receptors protect from development of prostatic intra-epithelial neoplasia in mice. [PDF]

open access: yesPLoS Genetics, 2013
LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines.
Aurélien J C Pommier   +11 more
doaj   +1 more source

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

open access: yes, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph   +14 more
core  

PSA and anthropometric measurements among Amazon Indians: an evaluation of the Parkatejê community [PDF]

open access: yes, 2003
OBJECTIVE: PSA (prostate-specific antigen) screening for early detection of prostate cancer in a native community is of great epidemiological importance.
Arruda, Homero Oliveira de [UNIFESP]   +3 more
core   +1 more source

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

open access: yeseFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie   +5 more
wiley   +1 more source

ABC of sexually transmitted infections - Main presentations of sexually transmitted infections in men [PDF]

open access: yes, 2004
This article is adapted from the fifth edition of the ABC ofSexually Transmitted Diseases, which is published by BMJBooks (www.bmjbooks.com).Some sexually transmitted infections, such as gonorrhoea and chlamydial infection, have different presentations ...
Richens, J
core  

Restoration of Immune Surveillance in Prostate Cancer Prevention by Sulforaphane in Hi‐Myc Mice

open access: yesMolecular Carcinogenesis, Volume 65, Issue 6, Page 677-686, June 2026.
ABSTRACT Oral administration of broccoli constituent sulforaphane (SFN) prevents prostate cancer development in preclinical mouse models. However, the mechanism(s) underlying prostate cancer prevention by SFN are not fully understood. In this study, we used a human relevant mouse model (Hi‐Myc mice) to demonstrate restoration of immune surveillance by ...
Krishna B. Singh   +3 more
wiley   +1 more source

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