Evaluation of immunoexpression and MDR1 promoter methylation levels in prostatic tissue samples [PDF]
Os objectivos deste estudo foram: (1) Determinar os níveis de metilação do promotor do MDR1 em tecido prostático com adenocarcinoma (CaP), neoplasia intraepitelial prostática de alto grau (HGPIN), hiperplasia benigna (BPH) e tecido morfologicamente ...
Costa, Vera L. +5 more
core
Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer. [PDF]
The introduction of serum Prostate Specific Antigen (PSA) testing nearly 30 years ago has been associated with a significant shift towards localized disease and decreased deaths due to prostate cancer.
Auman, Heidi +16 more
core +2 more sources
Early Cancer Detection: What's Going on and What's Next
Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley +1 more source
بررسی شيوع نئوپلازی داخل اپیتليالی با درجه بالا در نمونههای پروستات و همراهی آن با کانسر پروستات در مراجعهکنندگان به بيمارستان شهيد هاشمینژاد از سال 1378 لغايت 1379 [PDF]
هدف از اين مطالعه بررسی شيوع نئوپلازی داخل اپیتليالی پروستات با درجه بالا و همراهی آن با کانسر پروستات بوده است. در اين مطالعه اسلايدهای 137 مورد نمونه پروستات از سال 1378 لغايت 1379 در بيمارستان شهيد هاشمی نژاد که شامل بيوپسی سوزنی، توتال پروستاتکتومی
حاجیحسينی, امیرعباس +1 more
core
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Unsuspected Prostate Cancer After Cystoprostatectomy: A Comparison Between Two Periods in Taiwan
The incidence of and mortality rate from prostate cancer have been rising rapidly in Taiwan in recent years. Prostate specimens obtained during cystoprostatectomy may play a role in the study of prostate cancer evolution.
Jian-Ri Li +5 more
doaj +1 more source
Anticancer Molecular Mechanisms of Curcuminoids: An Updated Review of Clinical Trials
Curcuminoids remain one of the most studied dietary polyphenols as a cancer prevention and treatment agent. Inflammation and tumor progression are related to the NF‐κB signaling pathway, which is also suppressed by curcuminoids. Curcuminoids prevent the activation of a variety of signaling pathways, including the MAPK, PI3K/Akt, and NF‐kB pathways ...
Ushna Momal +14 more
wiley +1 more source
No effect of a high-fat diet on promotion of sex hormone-induced prostate and mammary carcinogenesis in the Noble rat model [PDF]
Department of Nursing and Health SciencesAuthor name used in this publication: I. F. F. BenzieAuthor name used in this publication: G.
Benzie, IFF +4 more
core +1 more source
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Objective: Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two pathological findings occasionally noted in prostate biopsies.
Sheng-Yung Tung +7 more
doaj +1 more source

