Results 111 to 120 of about 87,767 (313)

Treatment-related neuroendocrine prostatic carcinoma masquerading as a pheochromocytoma: an unusual presentation

Human Pathology Reports
Prostatic adenocarcinoma metastases to adrenal gland are rare and can be difficult to distinguish from primary adrenal neoplasms, particularly pheochromocytoma, especially in the post- treatment setting where neuroendocrine transformation is possible. We
Priscila Dias Goncalves, Peter M. Sadow, Miranda E. Machacek   +2 more
doaj   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Significance of immunohistochemistry in accurate characterization of malignant tumors [PDF]

, 2006
Background: To determine in a large series of surgical biopsies the role and significance of immunohistochemistry in the adequate and accurate characterization of malignant tumors.
Ahmed, Rashida, Ahmed, Zubair, Azad, Najamul Sahar, Bhurgari, Yasmeen, Hasan, Sheema, Kayani, Naila, Pervez, Shahid   +6 more
core   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

Single Potential Analysis of Cavernous Electric Activity in Impotent Patients: a Possible Diagnostic Method for Autonomic Cavernous Dysfunction and Cavernous Smooth Muscle Degeneration. [PDF]

, 1991
Allhoff, E. P., Anton, P., Djamilian, Mohamad H., Jonas, Udo, Riese, W. de, Stief, Christian Georg   +5 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Second brazilian consensus on the treatment of advanced prostate cancer: a SBOC-SBU-SBRT panel review

International Brazilian Journal of Urology
Prostate cancer is the second most common cancer and the fifth leading cause of cancer deaths. In Brazil, it is likewise the second most common cancer among men, second only to non-melanoma skin cancers.
Andre Deeke Sasse, Rodolfo Borges dos Reis, Lucas Mendes Nogueira, Fernando Cotait Maluf, Daniel Herchenhorn, Oren Smaletz, Volney Soares Lima, Fábio Schutz, Diogo Bastos, Evanius Garcia Wiermann, Igor Alexandre Protzner Morbeck, Leonardo Fontes Jardim, Vinicius Carrera Souza, Icaro Thiago Carvalho, Elton Trigo Teixeira Leite, Archimedes Nardozza Jr., Antonio Carlos Lima Pompeo, Francisco Bretas, Marcos Lima de Oliveira Leal, Marcus Vinicius Sadi, José Ricardo Tuma da Ponte, Gustavo F. Carvalhal   +21 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Efficient pathway for early detection of prostate cancer concluded from a 5-year prospective study [PDF]

, 1993
Allhoff, E. P., Gonnermann, O., Jonas, Udo, Liedke, S. G., Schneider, B., Stief, Christian Georg   +5 more
core   +1 more source