HISTOCHEMICAL STUDIES OF THE DEHYDROGENASE ACTIVITY IN PROSTATIC NEOPLASMS
Minoru Kanazawa +3 more
openalex +2 more sources
Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim +8 more
wiley +1 more source
Differentially Expressed miRNA of Prostate Cancer Compared with Benign Prostatic Hyperplasia Tissues: VAMP Associated Protein B Could Be Used for New Targets and Biomarkers of Prostate Cancer. [PDF]
Kim JH +9 more
europepmc +1 more source
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye +18 more
wiley +1 more source
Radical prostatectomy in metastatic prostate cancer: is there enough evidence? | Opinion: Yes
Walter Henriques da Costa +1 more
doaj +1 more source
Risk of postoperative urinary retention after sugammadex use in laparoscopic hernia repair: A matched cohort study of 23,444 cases. [PDF]
Hung KC +6 more
europepmc +1 more source
Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley +1 more source
Cytotoxicity of Esculetin Compared with Vinblastine and Paclitaxel in PC-3 Prostate Cancer Cells. [PDF]
García-Pérez AI +4 more
europepmc +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source

