Results 51 to 60 of about 211,414 (296)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Report of Frequency of Prostatic Adenocarcinoma Stage A in Patients Operated due to BPH

پزشکی بالینی ابن سینا, 2003
In this study 1192 cases were studied from 1986 to1996 in Imam Khomeini and Ekbatan hospitals of Hamadan province.           75 cases were found having pathologic stage A cancer (occult cancer).
Hooshang
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Metabolic syndrome and prostatic disease: potentially role of polyphenols in preventive strategies. A review

International Brazilian Journal of Urology, 2016
Benign prostatic hyperplasia and prostate cancer are two common urological diseases of the elderly. Scientific community has always looked for a link that could explain the correlation between the two diseases and the role of chronic inflammation in the ...
Tommaso Castelli, Giorgio Ivan Russo, Giulio Reale, Salvatore Privitera, Mario Chisari, Eugenia Fragalà, Vincenzo Favilla, Sebastiano Cimino, Giuseppe Morgia   +8 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Effect of heat exposure on viability and contractility of cultured prostatic stromal cells [PDF]

, 2000
Objectives: Different thermotherapeutic modalities such as transurethral microwave therapy or transurethral needle ablation have been developed to provide effective alternatives to surgical management of benign prostate hyperplasia (BPH).
Corvin, Stefan, Maneschg, Christoph, Klocker, Helmut, Radmayr, Christian, Boesch, Simone, Bartsch, Georg   +5 more
core   +1 more source

The Integral Role and Clinical Significance of Metabolic Profiling in Prostate Cancer: A Narrative Review [PDF]

Journal of Urologic Oncology
Prostate cancer (PC) is the most commonly diagnosed malignancy among males worldwide. In recent years, there has been a need to find alternative methods for the early diagnosis of PC.
Valentin Nikolaevich Pavlov, Marat Fayazovich Urmantsev, Marat Radikovich Bakeev, Olalekan Samuel Akinyemi   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Minimal (Limited) Pseudohyperplastic Prostatic Adenocarcinoma in Needle Prostatic Biopsy

, 2017
Background. Study of minimum adenocarcinoma has been done almost exclusively on conventional acinar adenocarcinoma. Pseudohyperplastic adenocarcinoma can be confused with benign lesions because of its well-differentiated appearance and has not been ...
Leticia Bornstein-Quevedo, Jorge Albores-Saavedra, Julian Arista-Nasr, Braulio Martinez-Benitez, Alejandra Mijangos-Trejo   +4 more
core   +1 more source

S-100A1 is a reliable marker in distinguishing nephrogenic adenoma from prostatic adenocarcinoma

, 2009
Nephrogenic adenoma is a benign lesion that may occur at any site of the genitourinary tract, usually in association with previous urothelial injuries. Although its pathogenesis is still debated, recent studies seem to confirm its derivation from renal ...
Mura A, MARTIGNONI, Guido, Massarelli G, Cossu Rocca P, Giovannino Massarelli, Guido Martignoni, Paolo Cossu-Rocca, Antonella Festa, Mura, Antonica, Contini, Marcella, Albino Eccher, Cossu Rocca, Paolo Alessandro, Eccher, Albino, Marcella Contini, Matteo Brunelli, Festa, Antonella, Gobbo, Stefano, Massarelli, Giovannino, Pili, Francesca, Stefano Gobbo, Brunelli, Matteo, Francesca Pili, Antonica Mura   +22 more
core   +2 more sources