Results 261 to 270 of about 1,749,266 (388)

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Combined computational, rational, and empirical design of boiling-resistant keratinase. [PDF]

Appl Environ Microbiol
Yang Y, Luo Y, Ding Y, Yao Y, Liu J, Xu Z, Li Y, Li H, Gan F, Tang X-F, Tang B.   +10 more
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

A programmable genetic platform for engineering noninvasive biosensors. [PDF]

Sci Adv
Chacko AN, Dhanabalan KM, Wan J, Chien R, Anderson NT, Xu B, Pham K, Tiwari R, Mukherjee A.   +8 more
europepmc   +1 more source

Corrigendum: Pseudomonas aeruginosa Modulates the Antiviral Response of Bronchial Epithelial Cells

Frontiers in Immunology, 2020
Michael Sörensen, Michael Sörensen, Julia Kantorek, Lauren Byrnes, Sébastien Boutin, Sébastien Boutin, Marcus A. Mall, Marcus A. Mall, Felix Lasitschka, Felix Lasitschka, Heike Zabeck, Dao Nguyen, Dao Nguyen, Alexander H. Dalpke, Alexander H. Dalpke, Alexander H. Dalpke   +15 more
doaj   +1 more source

Monitoring Global Gene Expression of Proteases and Improvement of Human Lysozyme Production in thenptBGene Disruptant ofAspergillus oryzae [PDF]

, 2008
Shinya Kimura, Jun‐ichi Maruyama, Michio Takeuchi, Katsuhiko Kitamoto   +3 more
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Enhancing Yields and Extending Production Cycles of Bacteriocin from the Bacillus cereus Group Through the Optimization of Culture Conditions and Removal of Proteolytic Digestion. [PDF]

Microorganisms
Gao M, Ding J, Yang C, Liu S, Zeng H, Zeng X, Zhao D, Xin B.   +7 more
europepmc   +1 more source

Biochemical and Immunological Studies of Neutral Protease. Localization and Extraction in vivo.

, 1992
Yoshihiro Sei, Yukari Ogura, Dousei Higuchi, Iwao Takiuchi   +3 more
openalex   +2 more sources

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source