EFFECT OF DIFFERENT LEVELS AGROECOLOGICAL LOADS ON BIOCHEMICAL CHARACTERISTICS OF SOIL
Юг России: экология, развитие, 2017 Aim. To study the effect of different levels of agri-environmental loads on the enzymatic activity of the soil.Methods. Isolation of soil fauna was conducted by thermogradient.
A. V. Shchur +2 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionPseudomonas aeruginosa causes vision threatening keratitis. The LasR transcription factor regulates virulence factors in response to the quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone. P.
Robert M. Q. Shanks +16 more
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Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. [PDF]
, 2018 Viruses are underrepresented as targets in pharmacological screening efforts, given the difficulties of devising suitable cell-based and biochemical assays.
Duggan, Brendan M +8 more
core +3 more sources
Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase
Viruses, 2022 Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the pol genes of retroviruses. We reported recently that HIV-1 RT and IN need to be supplied as the pol precursor intermediates, in which RT and IN are in fusion form (RTIN) to exert ...
Takao Masuda +5 more
doaj +1 more source
LIMITED PROTEOLYSIS OF FIBRINOGEN BY PROTEASE OF Gloydius halys halys SNAKE VENOM [PDF]
Biotechnologia Acta, 2021 Aim. One of the approaches for studying structure and functions of proteins is their limited proteolysis. Proteolytic fragments of macromolecules can preserve the biological activity and can be used for the study of their structural and functional ...
Ye. M. Stohnii +6 more
doaj +1 more source
Selective function-blocking monoclonal human antibody highlights the important role of membrane type-1 matrix metalloproteinase (MT1-MMP) in metastasis. [PDF]
, 2016 The invasion-promoting MT1-MMP is a cell surface-associated collagenase with a plethora of critical cellular functions. There is a consensus that MT1-MMP is a key protease in aberrant pericellular proteolysis in migrating cancer cells and, accordingly, a
Cieplak, Piotr +5 more
core +1 more source
Inhibition of SARS-CoV 3CL protease by flavonoids
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required.
S. Jo, Suwon Kim, D. Shin, Mi‐Sun Kim
semanticscholar +1 more source
Endocan in Acute Leukemia: Current Knowledge and Future Perspectives
Biomolecules, 2022 Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several human malignancies, and high expression (high serum/plasma levels or tumor ...
Håkon Reikvam +5 more
doaj +1 more source
MALT1 proteolytic activity suppresses autoimmunity in a T cell intrinsic manner [PDF]
, 2019 MALT1 is a central signaling component in innate and adaptive immunity by regulating NF-kappa B and other key signaling pathways in different cell types. Activities of MALT1 are mediated by its scaffold and protease functions.
Baens, Mathijs +7 more
core +2 more sources
Cases inefficient antiretroviral therapy for HIV-1 in children
Журнал инфектологии, 2017 Aim. Study cases virologic failure ART HIV-1 in children.Materials and methods. The blood plasma samples of 6 patients with HIV infection were used, identified under 1 year of life, from the North-West Federal District of the Russian Federation, received
Yu. V. Ostankova +3 more
doaj +1 more source