Results 21 to 30 of about 1,086,799 (301)

A rise in the frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionPseudomonas aeruginosa causes vision threatening keratitis. The LasR transcription factor regulates virulence factors in response to the quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone. P.
Robert M. Q. Shanks, Sarah Atta, Nicholas A. Stella, Chollapadi V. Sundar-Raj, John E. Romanowski, Arman S. Grewal, Hazel Q. Shanks, Sonya M. Mumper, Deepinder K. Dhaliwal, Alex Mammen, Jake D. Callaghan, Rachel C. Calvario, Eric G. Romanowski, Regis P. Kowalski, Michael E. Zegans, Michael E. Zegans, Vishal Jhanji   +16 more
doaj   +1 more source

LIMITED PROTEOLYSIS OF FIBRINOGEN BY PROTEASE OF Gloydius halys halys SNAKE VENOM [PDF]

Biotechnologia Acta, 2021
Aim. One of the approaches for studying structure and functions of proteins is their limited proteolysis. Proteolytic fragments of macromolecules can preserve the biological activity and can be used for the study of their structural and functional ...
Ye. M. Stohnii , A. V. Rebriev , O. V. Hornytska, O. Yu. Slominskiy , O. P. Kostiuchenko, K. P. Klymenko , V. O. Chernyshenko   +6 more
doaj   +1 more source

EFFECT OF DIFFERENT LEVELS AGROECOLOGICAL LOADS ON BIOCHEMICAL CHARACTERISTICS OF SOIL

Юг России: экология, развитие, 2017
Aim. To study the effect of different levels of agri-environmental loads on the enzymatic activity of the soil.Methods. Isolation of soil fauna was conducted by thermogradient.
A. V. Shchur, D. V. Vinogradov, V. P. Valckho   +2 more
doaj   +1 more source

Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase

Viruses, 2022
Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the pol genes of retroviruses. We reported recently that HIV-1 RT and IN need to be supplied as the pol precursor intermediates, in which RT and IN are in fusion form (RTIN) to exert ...
Takao Masuda, Osamu Kotani, Masaru Yokoyama, Yuya Abe, Gota Kawai, Hironori Sato   +5 more
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Protease-inhibitor interaction sites nomenclature

, 2023
Protease specificity pockets interacting with corresponding inhibitor binding ...
Annika W. Nonboe (15422756)
core   +1 more source

Endocan in Acute Leukemia: Current Knowledge and Future Perspectives

Biomolecules, 2022
Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several human malignancies, and high expression (high serum/plasma levels or tumor ...
Håkon Reikvam, Kimberley Joanne Hatfield, Øystein Wendelbo, Roald Lindås, Philippe Lassalle, Øystein Bruserud   +5 more
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Peroxisomal Proteostasis Involves a Lon Family Protein That Functions as Protease and Chaperone [PDF]

, 2012
Proteins are subject to continuous quality control for optimal proteostasis. The knowledge of peroxisome quality control systems is still in its infancy. Here we show that peroxisomes contain a member of the Lon family of proteases (Pln).
Kikhney, Alexey, Roermund, Carlo W.T. van,, van Roermund, C. W. T., Opalinski, L., Kikhney, A., Williams, Chris,, de Boer, R., Veenhuis, Marten, Kikhney, Alexey,, de Boer, Rinse, Williams, C., Williams, Chris, Opalinski, Lukasz, Bartoszewska, M., Klei, Ida J. van der,, van der Klei, Ida J., Boer, Rinse de,, Opaliński, Łukasz,, van der Klei, I. J., van Roermund, Carlo W. T., Veenhuis, Marten,, Veenhuis, M., van der Klei, Ida J.; id_orcid, Bartoszewska, Magdalena, Bartoszewska, Magdalena,   +24 more
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Cases inefficient antiretroviral therapy for HIV-1 in children

Журнал инфектологии, 2017
Aim. Study cases virologic failure ART HIV-1 in children.Materials and methods. The blood plasma samples of 6 patients with HIV infection were used, identified under 1 year of life, from the North-West Federal District of the Russian Federation, received
Yu. V. Ostankova, A. V. Semenov, M. A. Churina, A. A. Totolian   +3 more
doaj   +1 more source

Dermatophyte infection: from fungal pathogenicity to host immune responses

Frontiers in Immunology, 2023
Dermatophytosis is a common superficial infection caused by dermatophytes, a group of pathogenic keratinophilic fungi. Apart from invasion against skin barrier, host immune responses to dermatophytes could also lead to pathologic inflammation and tissue ...
Ruixin Deng, Ruixin Deng, Ruixin Deng, Ruixin Deng, Xiaowen Wang, Xiaowen Wang, Xiaowen Wang, Xiaowen Wang, Ruoyu Li, Ruoyu Li, Ruoyu Li, Ruoyu Li   +11 more
doaj   +1 more source

The role of the HIV-1 protease substrate in therapy resistance [PDF]

, 2015
In Switzerland and Germany up to a half of the first-line regimens include protease inhibitors (PIs) [1, 2]. Although in the Swiss HIV Cohort Study (SHCS) most patients under antiretroviral therapy (ART) have suppressed viral loads [3], every third ...
Kletenkov, Konstantin
core   +1 more source