Results 41 to 50 of about 1,086,799 (301)

Proteases, Protease-Activated Receptors, and Atherosclerosis [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2018
Coagulation activation by the TF (tissue factor) pathway plays pivotal roles in triggering platelets and precipitating acute coronary syndromes. Although dual antiplatelet therapy is effective in secondary cardiovascular prevention, combining platelet antagonism with low-dose aspirin and the oral coagulation FXa antagonist rivaroxaban has a synergistic
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Innovative Raw Material for Crackers: Unhairing Durable Dry Salt-Cured Skin with Elephant Grass IMO

open access: yesAndalasian Livestock
Dry salt-cured skin is an alternative material for standard shrimp crisp skin, but it is difficult to discard to discard hair. The alternative is to use indigenous microorganisms (IMO) of elephants grass (Pennisetum purpureum), which contain protease ...
Ari Muslim Ramadhan, Deni Novia
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Potensi protease bacillus subtilis natto sebagai pengempuk daging [PDF]

open access: yes, 2006
Kualitas daging yang akan dikonsumsi dapat ditingkatkan dengan pemberian enzim protease. Penelitian ini bertujuan untuk mempelajari pengemupkan daging sapi dengan menggunakan enzim protease dari B subtilis natto (B.natto).
Ferdian, Helmi
core  

Entrapment of protease from Bacillus sp. in polyvinyl alcohol hydrogels

open access: yesThe European Chemistry and Biotechnology Journal
This study highlights the effective immobilization of protease from Bacillus sp. in polyvinyl alcohol hydrogels and its characterization. Both free and entrapped proteases exhibited optimal activity at pH 8.0 and 55°C, indicating that the immobilization
Fatih Mehmet Hasbek, Deniz Yildirim
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Presenilin-1 Familial Alzheimer Mutations Impair γ-Secretase Cleavage of APP Through Stabilized Enzyme–Substrate Complex Formation

open access: yesBiomolecules
Familial Alzheimer’s disease (FAD) is caused by dominant missense mutations in amyloid precursor protein (APP) and presenilin-1 (PSEN1), the catalytic component of γ-secretase that generates amyloid β-peptides (Aβ) from the APP C-terminal fragment C99 ...
Sujan Devkota   +2 more
doaj   +1 more source

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