Results 191 to 200 of about 3,573,509 (380)

Increased frequency of the MZ phenotype of alpha-1-protease inhibitor in juvenile chronic polyarthritis. [PDF]

, 1977
P Arnaud, R M Galbraith, W. Pagé Faulk
openalex   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

, 1978
Mario Ascoli, David Puett
openalex   +1 more source

Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation

Nature Chemical Biology, 2022
Bryan J. Fraser, S. Beldar, A. Seitova, A. Hutchinson, D. Mannar, Yanjun Li, Daniel Kwon, Ruiyan Tan, Ryan P. Wilson, K. Leopold, S. Subramaniam, L. Halabelian, C. Arrowsmith, F. Bénard   +13 more
semanticscholar   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

EFFECT OF PROTEASE INHIBITORS OF ACTINOMYCETES ON LYSOSOMAL PEPTIDE-HYDROLASES FROM SWINE LIVER

, 1971
Hiroh Ikezawa, TOMIO TAKEUCHI, HAMAO UMEZAWA, TAKAAKI AOYAGI   +3 more
openalex   +2 more sources

Electric Pulse Regulated MXene Based Nanozymes for Integrative Bioelectricity Immuno‐Cancer Therapy

Advanced Functional Materials, EarlyView.
MXenzyme‐mediated bioelectricity cancer therapy (MXenzyme‐BECT) enhances cancer cell death through irreversible depolarization, ion channel disruption, ROS generation, and immunogenic cell death. Computational simulations reveal the electrical mechanisms by which MXenzyme acts on single cells and support to predict treatment parameters. Next‐generation
Sanghee Lee, Seongchan Kim, Eui‐Sang Yu, Sian Lee, Min Jun Ko, Hyojin Lee, Dong‐Hyun Kim   +6 more
wiley   +1 more source

Structure of the oligosaccharide chains in human alpha 1-protease inhibitor.

, 1979
Leslie Hodges-Gallagher, Roger A. Laine, S.K. Chan   +2 more
openalex   +1 more source

Human Plasmin and Protease Inhibitors: Interaction in a Whole Plasma System [PDF]

, 1977
Robert F. Highsmith, Camilla Burnett, C.J. Weirich   +2 more
openalex   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source