Results 201 to 210 of about 440,726 (262)

Evaluating therapeutic plasma exchange and protease inhibitors as mechanisms to reduce soluble mesothelin. [PDF]

Sci Rep
Smith KER, Ayers-Ringler JR, Orme JJ, Lucien F, Kim Y, Winters JL, Mansfield AS.   +6 more
europepmc   +1 more source

Plasma with Added Protease Inhibitors Improves Alpha- and Beta-CGRP Measurement Compared to Serum: Towards a Reliable Biomarker for Chronic Migraine. [PDF]

Int J Mol Sci
de la Guerra-Sasián L, Gárate G, Madera J, Pérez-Pereda S, Pascual-Mato M, González-Quintanilla V, Pascual J, Muñoz-San Martín M.   +7 more
europepmc   +1 more source

Statine-based peptidomimetics as SARS-CoV-2 Papain-like protease inhibitors: in Silico and in vitro studies. [PDF]

Sci Rep
Pimentel RDP, Camargo PG, de A Azevedo PHR, Constant LEC, da Silva Costa S, Allonso D, Rodrigues CR, Albuquerque MG, Dias LRS, Muri EMF, da Silva Lima CH.   +10 more
europepmc   +1 more source

Machine learning-driven docking of diverse DDAs as promising cysteine protease inhibitors targeting Mpox virus. [PDF]

In Silico Pharmacol
Alotaibi BS, Ahmad I, Almutairy B, Alkhammash A, Alsaiari AA, Khan K, Burki S.   +6 more
europepmc   +1 more source

Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages. [PDF]

Parasit Vectors
de Almeida Machado P, Gomes PS, Coimbra ES, de Matos Guedes HL.   +3 more
europepmc   +1 more source

Corrigendum to "Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease". [PDF]

Ther Adv Infect Dis
europepmc   +1 more source

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Protease Inhibitors in the Clinic

Medicinal Chemistry, 2005
This review describes the clinical status (based on available information) of experimental drugs that inhibit enzymes called proteases, or more precisely a sub-class of proteases called peptidases that catalyse the hydrolysis of polypeptide main chain amide bonds.
Abbenante, Giovanni, Fairlie , David P.
openaire   +4 more sources

Bacterial protease inhibitors

Medicinal Research Reviews, 2002
AbstractSerine‐, cysteine‐, and metalloproteases are widely spread in many pathogenic bacteria, where they play critical functions related to colonization and evasion of host immune defenses, acquisition of nutrients for growth and proliferation, facilitation of dissemination, or tissue damage during infection. Since all the antibiotics used clinically
SUPURAN, CLAUDIU TRANDAFIR, SCOZZAFAVA, ANDREA, B. W. Clare   +2 more
openaire   +3 more sources

Design of protease inhibitors

Biopolymers, 1981
AbstractThere is a general parallelism in the strategy followed in the design of hormonal peptide analogs and protease inhibitors. However, in the latter, one more dimension has been added with the development of mechanism‐based inhibitors, a dimension that is not yet available for hormonal peptides because of the lack of knowledge about receptor ...
M A, Ondetti, D W, Cushman
openaire   +2 more sources

Proteases and protease inhibitors in cancer

Acta Histochemica, 1998
The second conference on 'Proteases and protease inhibitors in cancer' was organized by the American Association for Cancer Research (AACR) and Acta Pathologica Microbiologica et Immunologica Scandinavica (APMIS). To understand the role of proteinases and to develop relevant synthetic inhibitors to stop or slow the progression of cancer, an integrated ...
openaire   +4 more sources