Results 251 to 260 of about 695,446 (323)

Statine-based peptidomimetics as SARS-CoV-2 Papain-like protease inhibitors: in Silico and in vitro studies. [PDF]

Sci Rep
Pimentel RDP, Camargo PG, de A Azevedo PHR, Constant LEC, da Silva Costa S, Allonso D, Rodrigues CR, Albuquerque MG, Dias LRS, Muri EMF, da Silva Lima CH.   +10 more
europepmc   +1 more source

IN SILICO COMPUTATIONAL SCREENING OF PHYTOCONSTITUENTS OF POLYHERBAL FORMULATION SUKKUMALLI KASHAYAM AGAINST MPRO, SPIKE PROTEIN AND TMPRSS2 PROTEASE INHIBITOR FOR SARS-COV-2

openalex   +1 more source

Twenty-eight Year Old HIV Positive Male Patient with Ergotism. Interaction of Ergot-alkaloids and Protease-inhibitors

, 2005
Wolfgang Mlekusch, Martin Schillinger, E Minar   +2 more
openalex   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Isolation and In Vitro Activity of Sesquiterpene Lactones from <i>Eremanthus crotonoides</i> as SARS-CoV-2 Protease Inhibitors and Cytotoxic Agents. [PDF]

Molecules
de Moura PHB, Ximenes NGDR, Santos BB, Leal CM, Constant LEC, Costa SDS, Pinto SC, Muzitano MF, Allonso D, Wessjohann LA, Leal ICR.   +10 more
europepmc   +1 more source

1P079 An evaluation method of in silico screening using HIV-1 protease and inhibitor

, 2004
Jun Nomura, Masahiro Sakurai
openalex   +2 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

<i><b>N</b></i>-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity. [PDF]

J Med Chem
Ghoshal A, Sears JD, Hossain MA, Tse EG, Howell S, Burdick JE, Morales NL, Martinez SA, Law I, Streblow ZJ, Streblow DN, Couñago RM, Moorman NJ, Heise MT, Willson TM.   +14 more
europepmc   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

Advanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar, Peifu Cheng, Tugce Dogruel, Maxsam Donta, Juhyung Jung, Naomi A. Asante, Donald S. Sakaguchi, Surya K. Mallapragada, Piran R. Kidambi, Metin Uz   +9 more
wiley   +1 more source