Results 251 to 260 of about 3,573,509 (380)

The effects of the protease inhibitor, aprotinin, on the course of shock induced by endotoxin in cats [PDF]

, 1985
B. Hughes, J. R. Parratt
openalex   +1 more source

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

Advanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra, Kai Yu, Jason Rogalski, Taylor Olivia Da Silva, Parisa Golesorkhi, Madeleine Goldstein, Dana V. Devine, Jayachandran N. Kizhakkedathu   +7 more
wiley   +1 more source

Fetal-Specific Forms of α1-Protease Inhibitors in Mouse Plasma [PDF]

, 1987
Salim Nathoo, Thomas H. Finlay
openalex   +1 more source

Molecular Mechanisms of Extracellular Vesicle Biogenesis and Their Impact on the Design of Custom EVs

Advanced Healthcare Materials, EarlyView.
Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz, Paulo Pereira, João Vasco Ferreira   +2 more
wiley   +1 more source

Investigation of the activity of 4-aminoquinolines as cysteine protease inhibitors with application in the treatment of Chagas disease. [PDF]

Mem Inst Oswaldo Cruz
Sheu-Idrees R, Marques GVL, Santana PAL, Diniz LA, Resende DM, Odoma S, Olorunshola O, Ferreira RS, Murta SMF, Maltarollo VG, de Oliveira RB.   +10 more
europepmc   +1 more source

Additive protection of aprotinin, protease inhibitor to cold cardioplegia from ischemic myocardium.

, 1980
Makoto Sunamori, Jun Amano, Takaaki Kameda, Takao Okamura, Masayoshi Ozeki, Akio Suzuki   +5 more
openalex   +2 more sources

Immunosuppressive Cytokine‐Tethered Hydrogel for Treating Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
An injectable hydrogel is developed by chemically tethering IL‐4, an immunosuppressive cytokine, to a hyaluronic acid‐based backbone. The hydrogel reduces joint friction and exerts immunomodulatory effects. In a rheumatoid arthritis (RA) mouse model, it reduced inflammation, preserved cartilage, and promoted anti‐inflammatory immune responses.
Woojin Back, Moonkyoung Jeong, Huyen‐Thao Le, Ji‐Ho Park   +3 more
wiley   +1 more source

Effects of Trichinella spiralis and its serine protease inhibitors on intestinal mucosal barrier function. [PDF]

Vet Res
Wang R, Zhang Y, Li Z, Zhen J, Li Q, Zhang Q, Yang Y, Liu X, Lu Y.   +8 more
europepmc   +1 more source

Role of PMN elastase on ischemic myocardial injury in evolving myocardial infarction: Correlation with clinical parameters and intervention by protease inhibitor ulinastatin.

, 1989
Shinichiro Shimai, Teruo Takano, Yoshihiko Seino, Keiji Tanaka, Hirokazu Hayakawa   +4 more
openalex   +2 more sources

Protease inhibitors as therapeutic agents

, 2014
Proteases are involved in a high number of diseases, and thus, are relevant targets. For that reason our main goal was the discovery of protease inhibitors as therapeutic agents. We focused our study in four proteases: dipeptidyl peptidase IV (diabetes mellitus type 2), prolyl oligopeptidase (cognitive disorders) and cathepsins L and B (cancer).For the
openaire   +2 more sources