Results 201 to 210 of about 558,985 (342)

Subtilisin NAT, a subtilisin-like serine protease present in fermented soybean “natto” extract, inhibits <i>Streptococcus mutans</i> biofilm formation

, 2021
Tomoki Yokoyama, Tomoyo Nakamura, Manami Kimijima, Kengo Mandokoro, Mizuki Tokumaru, Ayami Takatsuka, Naoki Narisawa, Rika Kobayashi, Fumio TAKENAGA   +8 more
openalex   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Improved genome assembly of Onygena corvina, a keratin-degrading fungus. [PDF]

BMC Res Notes
Pavale S, Eijsink VGH, La Rosa SL.
europepmc   +1 more source

Medicinal chemistry insights of molecular docking and cell permeability mechanism of phytoconstituents present in Mimosa pudica as NS2B-NS3 protease inhibitors against dengue virus [PDF]

Santosh Prasad Chaudhary Kurmi, Shankar Thapa, Ammar A. Razzak Mahmood, Ashok Kumar Murav, Mahalakshmi Suresha Biradar, Nina Bhagyanath, S.K. Maurya   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Thermostable Proteases from <i>Geobacillus</i>: Production, Characterization, Structural Stability Mechanisms and Biotechnological Applications. [PDF]

Microorganisms
Wang M, Wang JW, Cheng JH.
europepmc   +1 more source

Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases.

, 1995
Vicença Ustrell, G Pratt, Martin Rechsteiner   +2 more
openalex   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Partial characterization of a cysteine protease inhibitor of Plasmodium vivax. [PDF]

Parasites Hosts Dis
Võ TC, Kang JM, Lê HG, Na BK.
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source