Results 241 to 250 of about 393,592 (390)

The Proteasome: Paradigm of a Self-Compartmentalizing Protease [PDF]

open access: bronze, 1998
Wolfgang Baumeister   +3 more
openalex   +1 more source

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

open access: yesAdvanced Science, EarlyView.
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng   +10 more
wiley   +1 more source

Cypin regulates K63-linked polyubiquitination to shape synaptic content. [PDF]

open access: yesSci Adv
Gandu SR   +6 more
europepmc   +1 more source

Proteasome Structure and Assembly.

open access: yesJournal of Molecular Biology, 2017
Lauren Budenholzer   +3 more
semanticscholar   +1 more source

Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Overcoming platinum resistance in high‐grade serous ovarian cancer (HGSOC) is critical for improving outcomes. This study identifies lncRNA CATED, elevated in platinum‐resistant small extracellular vesicles (sEVs) and tumors, which drives cisplatin resistance by enhancing DHX36 SUMOylation, boosting RAP1A translation, and activating MAPK signaling ...
Yi Liu   +7 more
wiley   +1 more source

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome [PDF]

open access: yes, 2017
Choudhury, Rajarshi   +8 more
core   +2 more sources

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